Evidence map›Paper›PMID 26748759›Full record

ReviewCellular and molecular life sciences : CMLS2016

No longer a nuisance: long non-coding RNAs join CENP-A in epigenetic centromere regulation.

Silvana Rošić, Sylvia Erhardt

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
17.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. DNABERT-based explainable lncRNA identification in plant genome assemblies.Computational and structural biotechnology journal · 2023
    Article
  4. Molecular Dynamics and Evolution of Centromeres in the Genus Equus.International journal of molecular sciences · 2022
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. FunctionalFrontiers in plant science · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Silvana RošićMedical Research Council Clinical Sciences Centre, Imperial College London, London, UK.
Sylvia ErhardtZMBH, DKFZ-ZMBH-Alliance and CellNetworks Excellence Cluster, University of Heidelberg, Im Neuenheimer Feld 282, 69120, Heidelberg, Germany. s.erhardt@zmbh.uni-heidelberg.de.
DKFZ-ZMBH Alliance · DEMedical Research Council · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Centromeres represent the basis for kinetochore formation, and are essential for proper chromosome segregation during mitosis. Despite these essential roles, centromeres are not defined by specific DNA sequences, but by epigenetic means. The histone variant CENP-A controls centromere identity epigenetically and is essential for recruiting kinetochore components that attach the chromosomes to the mitotic spindle during mitosis. Recently, a new player in centromere regulation has emerged: long non-coding RNAs transcribed from repetitive regions of centromeric DNA function in regulating centromeres epigenetically. This review summarizes recent findings on the essential roles that transcription, pericentromeric transcripts, and centromere-derived RNAs play in centromere biology.

Indexed as

EpigenomicsAutoantigensCentromereCentromere Protein AChromatinChromosomal Proteins, Non-HistoneHumansKinetochoresMitosisRNA, Long NoncodingAutoantigensCENPA protein, humanCentromere Protein AChromatinChromosomal Proteins, Non-HistoneRNA, Long NoncodingCentromereEpigeneticsKinetochoreLong non-coding RNAMitosisTranscription

Identifiers

PMID26748759
PMCPMC11108473
OpenAlexW2233209699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.