Evidence map›Paper›PMID 26748550›Full record

ArticleTransboundary and emerging diseases2016

Highly Pathogenic Avian Influenza Virus A/H5N1 Infection in Vaccinated Meat Duck Flocks in the Mekong Delta of Vietnam.

N V Cuong, V N T Truc, N T Nhung, T T Thanh, T T B Chieu, T Q Hieu, N T Men, H H Mai, H T Chi, M F Boni and 4 more

Abstract read
In one paragraph

Article in Transboundary and emerging diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Understanding and controlling pandemic influenza.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

N V CuongOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hospital for Tropical Disease, Ho Chi Minh City, Vietnam.
V N T TrucOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hospital for Tropical Disease, Ho Chi Minh City, Vietnam.
N T NhungOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hospital for Tropical Disease, Ho Chi Minh City, Vietnam.
T T ThanhOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hospital for Tropical Disease, Ho Chi Minh City, Vietnam.
T T B ChieuOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hospital for Tropical Disease, Ho Chi Minh City, Vietnam.
T Q HieuSub-Department of Animal Health, Tien Giang Province, Vietnam.
N T MenSub-Department of Animal Health, Tien Giang Province, Vietnam.
H H MaiSub-Department of Animal Health, Tien Giang Province, Vietnam.
H T ChiSub-Department of Animal Health, Tien Giang Province, Vietnam.
M F BoniOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hospital for Tropical Disease, Ho Chi Minh City, Vietnam.
H R van DoornOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hospital for Tropical Disease, Ho Chi Minh City, Vietnam.
G E ThwaitesOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hospital for Tropical Disease, Ho Chi Minh City, Vietnam.
J J Carrique-MasOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hospital for Tropical Disease, Ho Chi Minh City, Vietnam.
N T HoaOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hospital for Tropical Disease, Ho Chi Minh City, Vietnam.

Funding

Wellcome Trust
6 · The paper itself

Abstract

We investigated episodes of suspected highly pathogenic avian influenza (HPAI)-like illness among 12 meat duck flocks in two districts in Tien Giang province (Mekong Delta, Vietnam) in November 2013. In total, duck samples from 8 of 12 farms tested positive for HPAI virus subtype A/haemagglutinin 5 and neuraminidase 1 (H5N1) by real-time RT-PCR. Sequencing results confirmed clade of 2.3.2.1.c as the cause of the outbreaks. Most (7/8) laboratory-confirmed positive flocks had been vaccinated with inactivated HPAI H5N1 clade 2.3.4 vaccines <6 days prior to onset of clinical signs. A review of vaccination data in relation to estimated production in the area suggested that vaccination efforts were biased towards larger flocks and that vaccination coverage was low [21.2% ducks vaccinated with two shots (range by district 7.4-34.9%)]. The low-coverage data, the experimental evidence of lack of cross-protection conferred by the currently used vaccines based on clade 2.3.4 together with the short lifespan of meat duck flocks (60-70 days), suggest that vaccination is not likely to be effective as a tool for control of H5N1 infection in meat duck flocks in the area.

Indexed as

DucksAnimalsDisease OutbreaksInfluenza A Virus, H5N1 SubtypeInfluenza in BirdsMeatVaccinationVietnamavian influenza virusduckH5N1one healthvaccineveterinary epidemiologyzoonoses

Identifiers

PMID26748550
PMCPMC4819680

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.