Evidence map›Paper›PMID 26747622›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2016

Long-term survival of an infant with an atypical teratoid/rhabdoid tumor following subtotal resection and low-cumulative dose chemotherapy: a case report.

Viktor Arnhold, Florian Oyen, Reinhard Schneppenheim, Hannes Haberl, Arend Koch, Michael C Frühwald, Pablo Hernáiz Driever

Abstract readCase Reports
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In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Viktor ArnholdDepartment of Pediatric Oncology/Hematology/BMT, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany. viktor.arnhold@charite.de.
Florian OyenDepartment of Pediatric Oncology and Hematology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Reinhard SchneppenheimDepartment of Pediatric Oncology and Hematology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Hannes HaberlDepartment of Pediatric Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Arend KochInstitute of Pathology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Michael C FrühwaldSwabian Children's Cancer Center, Children's Hospital Augsburg, Klinikum Augsburg, Augsburg, Germany.
Pablo Hernáiz DrieverDepartment of Pediatric Oncology/Hematology/BMT, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DEUniversität Hamburg · DEUniversity Hospital Augsburg · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAtypical teratoid/rhabdoid tumor (AT/RT) is an aggressive embryonal tumor of the central nervous system with a generally dismal prognosis, especially in patients younger than 12 months. DISCUSSION: We here describe the unusual case of an infant with AT/RT with long-term survival despite low-cumulative dose chemotherapy after subtotal resection. Due to a poor neurological situation and an unfavorable oncological prognosis, therapy was halted after two partial surgical resections and four of the nine chemotherapy courses recommended by the European Rhabdoid Registry, without the patient receiving either radiotherapy or high-dose chemotherapy. The patient is alive without evidence of disease 52 months after diagnosis.

conclusionThis case report highlights that independent prognostic factors are urgently needed for optimizing treatment stratification and preventing overtreatment.

Indexed as

Rhabdoid TumorAntineoplastic AgentsBrain NeoplasmsCombined Modality TherapyFemaleHumansInfantMagnetic Resonance ImagingNeurosurgical ProceduresAntineoplastic AgentsAT/RTChemotherapyChildhood cancerSMARCB1/Ini1

Identifiers

PMID26747622
OpenAlexW2231431688

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.