Evidence map›Paper›PMID 26746998›Full record

ArticleJournal of the American Heart Association2016

Simple Renal Cysts as Markers of Thoracic Aortic Disease.

Bulat A Ziganshin, Panagiotis Theodoropoulos, Mohammad N Salloum, Khaled J Zaza, Maryann Tranquilli, Hamid R Mojibian, Neera K Dahl, Hai Fang, John A Rizzo, John A Elefteriades

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Extent of Acute Type A Aortic Dissection in Patients With Organ Cysts.Interdisciplinary cardiovascular and thoracic surgery · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. The Correlation and Copathogenesis of Coronary Aortic Sandwich and Renal Cysts.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Surgical outcomes of acute type A aortic dissection in dialysis patients.General thoracic and cardiovascular surgery · 2019
    Article
  13. Thoracic aortic aneurysm: unlocking the "silent killer" secrets.General thoracic and cardiovascular surgery · 2019
    Review
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Bulat A ZiganshinAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (B.A.Z., P.T., M.N.S., K.J.Z., M.T., H.R.M., J.A.R., J.A.E.) Department of Surgical Diseases # 2, Kazan State Medical University, Kazan, Russia (B.A.Z.).
Panagiotis TheodoropoulosAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (B.A.Z., P.T., M.N.S., K.J.Z., M.T., H.R.M., J.A.R., J.A.E.).
Mohammad N SalloumAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (B.A.Z., P.T., M.N.S., K.J.Z., M.T., H.R.M., J.A.R., J.A.E.).
Khaled J ZazaAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (B.A.Z., P.T., M.N.S., K.J.Z., M.T., H.R.M., J.A.R., J.A.E.).
Maryann TranquilliAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (B.A.Z., P.T., M.N.S., K.J.Z., M.T., H.R.M., J.A.R., J.A.E.).
Hamid R MojibianAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (B.A.Z., P.T., M.N.S., K.J.Z., M.T., H.R.M., J.A.R., J.A.E.) Section of Vascular and Interventional Radiology, Yale University School of Medicine, New Haven, CT (H.R.M.).
Neera K DahlSection of Nephrology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT (N.K.D.).
Hai FangChina Center for Health Development Studies, Peking University, Beijing, China (H.F.).
John A RizzoAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (B.A.Z., P.T., M.N.S., K.J.Z., M.T., H.R.M., J.A.R., J.A.E.) Departments of Economics and Preventive Medicine, Stony Brook University, Stony Brook, NY (J.A.R.).
John A ElefteriadesAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT (B.A.Z., P.T., M.N.S., K.J.Z., M.T., H.R.M., J.A.R., J.A.E.).
Yale New Haven Hospital · USYale University · USPeking University · CNStony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThoracic aortic aneurysm is usually a clinically silent disease; timely detection is largely dependent upon identification of clinical markers of thoracic aortic disease (TAD); (bicuspid aortic valve, intracranial aortic aneurysm, bovine aortic arch, or positive family history). Recently, an association of simple renal cysts (SRC) with abdominal aortic aneurysm and aortic dissection was established. The aim of our study was to evaluate the prevalence of SRC in patients with TAD in order to assess whether the presence of SRC can be used as a predictor of TAD. METHODS AND

resultsWe evaluated the prevalence of SRC in 842 patients with TAD (64.0% males) treated at our institution from 2004 to 2013 and compared to a control group of patients (n=543; 56.2% males). Patients were divided into 4 groups: ascending aortic aneurysm (456; 54.2%); descending aortic aneurysm (86; 10.2%); type A aortic dissection (118; 14.0%); and type B aortic dissection (182; 21.6%). SRC were identified by abdominal computed tomography or magnetic resonance imaging of these patients. Prevalence of SRC is 37.5%, 57.0%, 44.1%, and 47.3% for patients with ascending aneurysm, descending aneurysm, type A dissection, and type B dissection, respectively. Prevalence of SRC in the control group was 15.3%. Prevalence of SRC was not significantly different between male and female aortic disease patients, despite reported general male predominance (2:1), which was also observed in our control group (1.7:1).

conclusionsThis study establishes an increased prevalence of SRC in patients with TAD. SRC can potentially be used as a marker for timely detection of patients at risk of TAD.

Indexed as

AdolescentAdultAgedAged, 80 and overAge DistributionAortic Aneurysm, ThoracicAortic DissectionAortographyConnecticutFemaleHumansKidney Diseases, CysticMagnetic Resonance AngiographyMaleMiddle AgedPrevalenceaortic dissectionmarkersimple renal cystthoracic aortic aneurysm

Identifiers

PMID26746998
PMCPMC4859353
OpenAlexW2257985724

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.