ReviewTrends in ecology & evolution2016
Complex Homology and the Evolution of Nervous Systems.
Review in Trends in ecology & evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- On the molecular basis of enduring memory in neurons, and cell fate in fibroblasts.Nucleic acids research · 2026Review
- Review
- Evolution of the Metazoan Protein Domain Repertoire Revealed by a Birth-Death-Gain Model.Journal of molecular evolution · 2025Article
- The ancient dialogue between brain and body.Current biology : CB · 2025Article
- EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis.eLife · 2025Article
- Review
- Incongruence in the phylogenomics era.Nature reviews. Genetics · 2023Review
- Peripheral and central employment of acid-sensing ion channels during early bilaterian evolution.eLife · 2023Article
- Genome Integrity and Neurological Disease.International journal of molecular sciences · 2022Review
- Humans, fish, spiders and bees inherited working memory and attention from their last common ancestor.Frontiers in psychology · 2022Article
- Elementary nervous systems.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Developmental processes in Ediacara macrofossils.Proceedings. Biological sciences · 2021Article
- Neural shutdown under stress: an evolutionary perspective on spreading depolarization.Journal of neurophysiology · 2020Review
- Direct Fit to Nature: An Evolutionary Perspective on Biological and Artificial Neural Networks.Neuron · 2020Review
- The evolution of brain structure captured in stereotyped cell count and cell type distributions.Current opinion in neurobiology · 2020Review
- Evolution of neuronal types and families.Current opinion in neurobiology · 2019Review
- Coherent directed movement toward food modeled inProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Conserved transcriptomic profiles underpin monogamy across vertebrates.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Comparative Principles for Next-Generation Neuroscience.Frontiers in behavioral neuroscience · 2019Article
- Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization.BMC neuroscience · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
We examine the complex evolution of animal nervous systems and discuss the ramifications of this complexity for inferring the nature of early animals. Although reconstructing the origins of nervous systems remains a central challenge in biology, and the phenotypic complexity of early animals remains controversial, a compelling picture is emerging. We now know that the nervous system and other key animal innovations contain a large degree of homoplasy, at least on the molecular level. Conflicting hypotheses about early nervous system evolution are due primarily to differences in the interpretation of this homoplasy. We highlight the need for explicit discussion of assumptions and discuss the limitations of current approaches for inferring ancient phenotypic states.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.