ArticleMolecular neurobiology2017
In Vitro Differentiation of Human iPS Cells into Neural like Cells on a Biomimetic Polyurea.
Article in Molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
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- Small Molecule Differentiate PDX1-Expressing Cells Derived from Human Endometrial Stem Cells on PAN Electrospun Nanofibrous Scaffold: Applications for the Treatment of Diabetes in Rat.Molecular neurobiology · 2020Article
- Maneuvering the Migration and Differentiation of Stem Cells with Electrospun Nanofibers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Review
- Differentiation of endometrial stem cells into insulin-producing cells using signaling molecules and zinc oxide nanoparticles, and three-dimensional culture on nanofibrous scaffolds.Journal of materials science. Materials in medicine · 2019Article
- The impact of the particle size of curcumin nanocarriers and the ethanol on beta_1-integrin overexpression in fibroblasts: A regenerative pharmaceutical approach in skin repair and anti-aging formulations.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2019Article
- Stimulation of Osteogenic Differentiation of Induced Pluripotent Stem Cells (iPSCs) Using Bioactive Glasses: AnFrontiers in bioengineering and biotechnology · 2019Article
- Interaction of iPSC-derived neural stem cells on poly(L-lactic acid) nanofibrous scaffolds for possible use in neural tissue engineering.International journal of molecular medicine · 2018Article
- The Role of Stem Cells in the Treatment of Cerebral Palsy: a Review.Molecular neurobiology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human-induced pluripotent stem cells (hiPSCs) have the pluripotency to differentiate into all three germ layers in vitro and have been considered potent candidates for regenerative medicine as an unlimited source of cells for therapeutic applications. Neural tissue engineering is an important area of research in the field of tissue-engineering especially for neurodegenerative disease. Here, we investigated the use of poly lactic acid/gelatin (PLA/gelatin) scaffold as three-dimensional (3D) system which increase neural cell differentiation. Through neural induction, neural-like cells (NLCs) were derived from hiPSCs on nanofibrous PLA/gelatin scaffold. Enhanced numbers of neural structures and staining of neural markers were observed with hiPS cell-seeded nanofibrous scaffolds when compared with control medium. The results revealed that hiPSCs attach and grow on the nanofibrous PLA/gelatin scaffold, and hiPSCs cultured on scaffold have the potential to differentiate in neuronal cells in the presence of growth factors. The result of this study may have impact in tissue engineering and cells-base therapy of neurodegenerative diseases and have a great potential for wide application.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.