Evidence map›Paper›PMID 26746606›Full record

ArticleInternational journal of pediatric otorhinolaryngology2016

Improved behavior after adenotonsillectomy in children with higher and lower IQ.

Seockhoon Chung, Elise K Hodges, Deborah L Ruzicka, Timothy F Hoban, Susan L Garetz, Kenneth E Guire, Barbara T Felt, James E Dillon, Ronald D Chervin, Bruno Giordani

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of pediatric otorhinolaryngology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00233194 (Identification of Sleep-Disordered Breathing in Children), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00233194 completednot on this map

Identification of Sleep-Disordered Breathing in Children

TypeobservationalSponsorUniversity of MichiganRan2005 to 2011Enrolled160ConditionsSleep, Sleep Apnea Syndromes, Sleep Disordered BreathingArmsObservational follow-up study of adenotonsillectomy
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Pediatric Obstructive Sleep Apnea: What's in a Name?Advances in experimental medicine and biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Seockhoon ChungSleep Disorders Center, Ann Arbor, MI, USA; Department of Neurology, Ann Arbor, MI, USA; Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea. Electronic address: schung@amc.seoul.kr.
Elise K HodgesNeuropsychology Section, Department of Psychiatry, Ann Arbor, MI, USA.
Deborah L RuzickaSleep Disorders Center, Ann Arbor, MI, USA; Department of Neurology, Ann Arbor, MI, USA.
Timothy F HobanSleep Disorders Center, Ann Arbor, MI, USA; Department of Pediatrics and Communicable Diseases, Ann Arbor, MI, USA.
Susan L GaretzSleep Disorders Center, Ann Arbor, MI, USA; Department of Otolaryngology/Head and Neck Surgery, Ann Arbor, MI, USA.
Kenneth E GuireDepartment of Biostatistics, Ann Arbor, MI, USA.
Barbara T FeltSleep Disorders Center, Ann Arbor, MI, USA; Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA.
James E DillonDepartment of Psychiatry, Central Michigan University College of Medicine, Saginaw, MI, USA.
Ronald D ChervinSleep Disorders Center, Ann Arbor, MI, USA; Department of Neurology, Ann Arbor, MI, USA.
Bruno GiordaniDepartment of Neurology, Ann Arbor, MI, USA; Neuropsychology Section, Department of Psychiatry, Ann Arbor, MI, USA.
Michigan Medicine · USCentral Michigan University · USUniversity of Michigan–Ann Arbor · USUniversity of Ulsan · KR

Funding

Sleep-Disordered Breathing and CPAP after Adenotonsillectomy in ChildrenR01HL105999 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHERVIN, RONALD D · 2012 to 2016
$3.2M
Identification of Sleep-Disordered Breathing in ChildrenR01HL080941 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHERVIN, RONALD D · 2004 to 2008
$2.7M
NHLBI NIH HHS R01 HL080941NHLBI NIH HHS R01 HL105999
6 · The paper itself

Abstract

objectivesTo examine whether high intellectual ability, in comparison to average or lower performance, reflects the consequences of sleep-disordered breathing and limits behavioral benefit observed 6 months after adenotonsillectomy.

methodsChildren aged 3-12 years (n=147) recruited from otolaryngology practices at two hospitals and assessed with Conners' Parent Rating Scales and an age range-appropriate intellectual measure, the Stanford-Binet Intelligence Scale at baseline and 6 months after clinically-indicated adenotonsillectomy. Subjects were classified as having high (IQ≥110), average (90≤IQ<110), or low (IQ<90) cognitive ability.

resultsAfter adenotonsillectomy, improvements in Conners' internalizing, externalizing, hyperactivity, and cognitive domains were observed across IQ groups (main effects for time, all p<0.01 or better), with no evidence for differential improvements among the groups (no significant time by IQ group interactions). The magnitude of behavioral improvement among children with high IQ resembled that observed among the other two groups. Changes in the Conners' domains were not significantly correlated with baseline IQ, age, socioeconomic status, body mass index z-score, or respiratory disturbance index.

conclusionBehavioral function can improve after adenotonsillectomy even among children with relatively high intellectual ability at baseline. Diagnosis and treatment with expectation of neurobehavioral benefit should be considered among high-performing children as readily as it is more traditionally among their lower-performing peers.

Indexed as

Child BehaviorIntelligenceAdenoidectomyAttention Deficit Disorder with HyperactivityChildChild, PreschoolFemaleHumansIntelligence TestsMaleSleep Apnea SyndromesTonsillectomyIntelligenceNeurobehavioral functionSleep apnea syndromeTonsillectomy

Identifiers

PMID26746606
PMCPMC4706995
OpenAlexW2159430041

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.