Evidence map›Paper›PMID 26746187›Full record

ReviewJournal of neurology, neurosurgery, and psychiatry2016

High-resolution intracranial vessel wall imaging: imaging beyond the lumen.

Matthew D Alexander, Chun Yuan, Aaron Rutman, David L Tirschwell, Gerald Palagallo, Dheeraj Gandhi, Laligam N Sekhar, Mahmud Mossa-Basha

Abstract readReview
In one paragraph

Review in Journal of neurology, neurosurgery, and psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Comparative meta-analysis of endovascular strategies for intracranial dissecting aneurysms: Flow diverters versus stents with or without coiling.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Pooled it
  2. Review
  3. Article
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  9. Intracranial vessel wall lesions on MRI: anatomical and pathological issues.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  10. Article
  11. High resolution 7T MR imaging in characterizing culprit intracranial atherosclerotic plaques.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matthew D AlexanderDepartment of Radiology, University of Washington, Seattle, Washington, USA.
Chun YuanDepartment of Radiology, University of Washington, Seattle, Washington, USA.
Aaron RutmanDepartment of Radiology, University of Washington, Seattle, Washington, USA.
David L TirschwellDepartment of Neurology, University of Washington, Seattle, Washington, USA.
Gerald PalagalloDepartment of Radiology, University of Washington, Seattle, Washington, USA.
Dheeraj GandhiDepartment of Radiology, Neurology and Neurosurgery, University of Maryland, Baltimore, Maryland, USA.
Laligam N SekharDepartment of Neurological Surgery, University of Washington, Seattle, Washington, USA.
Mahmud Mossa-BashaDepartment of Radiology, University of Washington, Seattle, Washington, USA.

Funding

3D WALLI: MR intracranial vessel wall imaging for stroke preventionR01NS092207 · NINDS · UNIVERSITY OF WASHINGTON · PI MOSSA-BASHA, MAHMUD, YUAN, CHUN · 2016 to 2019
$3.1M
3D WALLI: MR intracranial vessel wall imaging for stroke preventionR56NS092207 · NINDS · UNIVERSITY OF WASHINGTON · PI MOSSA-BASHA, MAHMUD, YUAN, CHUN · 2015 to 2015
$609k
NINDS NIH HHS R01 NS092207NINDS NIH HHS R56 NS092207
6 · The paper itself

Abstract

Accurate and timely diagnosis of intracranial vasculopathies is important due to significant risk of morbidity with delayed and/or incorrect diagnosis both from the disease process as well as inappropriate therapies. Conventional vascular imaging techniques for analysis of intracranial vascular disease provide limited information since they only identify changes to the vessel lumen. New advanced MR intracranial vessel wall imaging (IVW) techniques can allow direct characterisation of the vessel wall. These techniques can advance diagnostic accuracy and may potentially improve patient outcomes by better guided treatment decisions in comparison to previously available invasive and non-invasive techniques. While neuroradiological expertise is invaluable in accurate examination interpretation, clinician familiarity with the application and findings of the various vasculopathies on IVW can help guide diagnostic and therapeutic decision-making. This review article provides a brief overview of the technical aspects of IVW and discusses the IVW findings of various intracranial vasculopathies, differentiating characteristics and indications for when this technique can be beneficial in patient management.

Indexed as

Cerebral AngiographyDiffusion Magnetic Resonance ImagingImage Interpretation, Computer-AssistedMagnetic Resonance AngiographyCerebrovascular DisordersEndothelium, VascularHumansMuscle, Smooth, VascularSensitivity and SpecificityARTERIAL DISSECTIONCEREBROVASCULAR DISEASEMRAMRISTROKE

Identifiers

PMID26746187
PMCPMC5504758

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.