Evidence map›Paper›PMID 26746133›Full record

ReviewFertility and sterility2016

Experimental methods to preserve male fertility and treat male factor infertility.

Kathrin Gassei, Kyle E Orwig

Abstract readReview
In one paragraph

Review in Fertility and sterility, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Article
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  12. Cisplatin Induces Apoptosis in Mouse Neonatal Testes Organ Culture.International journal of molecular sciences · 2022
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Pathological Roles of Reactive Oxygen Species in Male Reproduction.Advances in experimental medicine and biology · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kathrin GasseiDepartment of Obstetrics, Gynecology and Reproductive Sciences and Magee-Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Kyle E OrwigDepartment of Obstetrics, Gynecology and Reproductive Sciences and Magee-Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Electronic address: orwigke@upmc.edu.

Funding

Transplant CoreP01HD075795 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI ORWIG, KYLE EDWIN · 2014 to 2018
$7.0M
Cellular Mechanisms of Chemotherapy-induced Male Infertility: Stem Cell or Niche?R01HD076412 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI ORWIG, KYLE EDWIN · 2014 to 2018
$3.0M
NICHD NIH HHS HD075795NICHD NIH HHS HD076412NICHD NIH HHS P01 HD075795NICHD NIH HHS R01 HD076412
6 · The paper itself

Abstract

Infertility is a prevalent condition that has insidious impacts on the infertile individuals, their families, and society, which extend far beyond the inability to have a biological child. Lifestyle changes, fertility treatments, and assisted reproductive technology (ART) are available to help many infertile couples achieve their reproductive goals. All of these technologies require that the infertile individual is able to produce at least a small number of functional gametes (eggs or sperm). It is not possible for a person who does not produce gametes to have a biological child. This review focuses on the infertile man and describes several stem cell-based methods and gene therapy approaches that are in the research pipeline and may lead to new fertility treatment options for men with azoospermia.

Indexed as

CryopreservationFertilityAge FactorsAnimalsFertility PreservationGenetic TherapyHumansInfertility, MaleMaleRisk FactorsSemen PreservationSpermatogenesisStem Cell TransplantationTestisazoospermiaculturede novo testicular morphogenesisFertilitygene therapygraftinginfertilitystem cellstransplantation

Identifiers

PMID26746133
PMCPMC4744139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.