Evidence map›Paper›PMID 26745827›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2016

Incidence of HIV Infection and Sexually Transmitted Infections and Related Risk Factors Among Very Young Men Who Have Sex With Men.

Robert Garofalo, Anna L Hotton, Lisa M Kuhns, Beau Gratzer, Brian Mustanski

Open access · greenAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 3 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 3 syntheses or guidelines pooled it, 110 citations in OpenAlex.

  1. Pooled it
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  3. Bias Adjustment Techniques Are Underutilized in HIV Sexual Risk Estimation: A Systematic Review.International journal of environmental research and public health · 2018
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  20. AIDS or HIV Education and Sexual Behaviors Among Adolescent Sexual Minority Males: National HIV Behavioral Surveillance, 3 U.S. Cities, 2015.AIDS education and prevention : official publication of the International Society for AIDS Education · 2023
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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Robert Garofalo*Division of Adolescent Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; †Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL; ‡Division of Infectious Diseases, John H. Stroger Hospital, Chicago, IL; §Howard Brown Health Center, Chicago, IL; and ‖Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Anna L Hotton
Lisa M Kuhns
Beau Gratzer
Brian Mustanski
National Institute on Drug Abuse · USLurie Children's Hospital · US

Funding

Syndemic Development and HIV Risk Among Vulnerable Young MenR01DA025548 · NIDA · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI GAROFALO, ROBERT, MUSTANSKI, BRIAN · 2009 to 2013
$3.5M
NIDA NIH HHS R01 DA025548NIDA NIH HHS R01DA025548
6 · The paper itself

Abstract

introductionThe HIV epidemic continues to disproportionately affect men who have sex with men (MSM) in the United States, with over a third of new infections in MSM occurring in younger men. Very few studies have reported on HIV and sexually transmitted infection (STI) incidence and related risks among younger MSM, particularly among minors under 18 years of age.

methodsData analyzed herein are from a longitudinal study of HIV risk among 450 very young MSM in Chicago aged 16 to 20, recruited via respondent-driven sampling and followed-up for 2 years, with annual HIV and STI testing. We report estimated cumulative HIV and STI incidence over the 24-month follow-up using Kaplan-Meier methods and evaluated associations with incident infections using Cox proportional hazards regression.

resultsThe final analytic sample was primarily non-white (83%); median age was 19; 25% of the sample was under age 18. Twenty-six new HIV infections were detected over 632 person-years of follow-up. HIV incidence was 4.11/100 person-years [95% confidence interval (CI): 2.80 to 6.04] and STI incidence was 6.22/100 person-years (95% CI: 4.54 to 8.51). Cumulative HIV incidence over 24 months of follow-up was 7.32% (95% CI: 5.05 to 10.57), with higher incidence among racial/ethnic minorities. In multivariate analyses, non-white race and recent sexual partner concurrency were associated with both HIV and STI infection; HIV testing history and sex with an HIV-positive partner were associated with increased risk of HIV infection. DISCUSSION: High rates of incident HIV infection and STIs among very young MSM and the relationship between incidence and race/ethnicity, concurrency and partner characteristics indicate potential focal points of future intervention and the need for continued vigilance.

Indexed as

AdolescentAdultChicagoChlamydia InfectionsGonorrheaHIV InfectionsHomosexuality, MaleHumansIntimate Partner ViolenceLongitudinal StudiesMaleMass ScreeningRisk FactorsSexual BehaviorSexual PartnersYoung Adult

Identifiers

PMID26745827
PMCPMC4837074
OpenAlexW2315554567

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.