Evidence map›Paper›PMID 26745730›Full record

ReviewJournal of photochemistry and photobiology. B, Biology2016

Infrared and skin: Friend or foe.

Daniel Barolet, François Christiaens, Michael R Hamblin

Abstract readReview
In one paragraph

Review in Journal of photochemistry and photobiology. B, Biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Effectiveness of Using the AOPT-LTL Technique for the Treatment of Melasma: A Clinical Study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026
    Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. [Skin damage caused by optical radiation beyond UV].Dermatologie (Heidelberg, Germany) · 2026
    Article
  10. Article
  11. Light-Activated Micromotors in Air Propelled by Thermal Convection.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Determination of the damaging effect of IR radiation on DNA by electrochemical methods and investigation of this effect in the presence of chitosan.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Article
  19. Article
  20. Photodynamic therapy on mRNA levels in bacteria.Lasers in medical science · 2024
    Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel BaroletDepartment of Medicine, Dermatology Division, McGill University, Montreal H3A 1A1, Canada; RoseLab Skin Optics Laboratory, LavalH7T 0G3, Canada. Electronic address: daniel.barolet@mcgill.ca.
François ChristiaensSaint-Maur-des-Fossés, 94100, France.
Michael R HamblinThe Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, United States; Department of Dermatology, Harvard Medical School, Boston, MA 02115, United States; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA 02139, United States.

Funding

Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8M
NIAID NIH HHS R01 AI050875NIAID NIH HHS R01AI050875
6 · The paper itself

Abstract

In the last decade, it has been proposed that the sun's IR-A wavelengths might be deleterious to human skin and that sunscreens, in addition to their desired effect to protect against UV-B and UV-A, should also protect against IR-A (and perhaps even visible light). Several studies showed that NIR may damage skin collagen content via an increase inMMP-1 activity in the same manner as is known for UVR. Unfortunately, the artificial NIR light sources used in such studies were not representative of the solar irradiance. Yet, little has been said about the other side of the coin. This article will focus on key information suggesting that IR-A may be more beneficial than deleterious when the skin is exposed to the appropriate irradiance/dose of IR-A radiation similar to daily sun exposure received by people in real life.IR-A might even precondition the skin--a process called photo prevention--from an evolutionary standpoint since exposure to early morning IR-A wavelengths in sunlight may ready the skin for the coming mid-day deleterious UVR. Consequently IR-A appears to be the solution, not the problem. It does more good than bad for the skin. It is essentially a question of intensity and how we can learn from the sun. © 2016 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Indexed as

Infrared RaysHumansLightMatrix Metalloproteinase 1Oxidative StressSkinSkin AgingTemperatureMatrix Metalloproteinase 1Infrared (IR)IR-AIrradianceMMP-1PhotobiomodulationPhotoprevention

Identifiers

PMID26745730
PMCPMC4745411

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.