Evidence map›Paper›PMID 26745682›Full record

ReviewJournal of child and adolescent psychopharmacology2016

Behavioral Interventions for Anger, Irritability, and Aggression in Children and Adolescents.

Denis G Sukhodolsky, Stephanie D Smith, Spencer A McCauley, Karim Ibrahim, Justyna B Piasecka

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Journal of child and adolescent psychopharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 80 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 4 pooled it
22.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02914951 naenrolling by invitationnot on this map

Cognitive-Behavioral Therapy for Disruptive Behavior in Children and Adolescents (An Open Pilot Study in Autism Spectrum Disorder)

TypeinterventionalSponsorYale UniversityRan2016 to 2026Enrolled6ConditionsAutism, Intellectual DisabilityArmsCognitive-Behavioral Therapy, Functional magnetic resonance imaging (fMRI)
NCT04654260 nacompletednot on this mapstarted 2020, after this paper: background citation

Behavior Therapy for Irritability and Aggression in Adolescents With Autism

TypeinterventionalSponsorYale UniversityRan2020 to 2026Enrolled65ConditionsAutism Spectrum Disorder, Irritability, Disruptive Behavior, AngerArmsBehavioral Therapy for Irritability in Autism, Psychoeducation and Supportive Therapy (PST)
3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 4 syntheses or guidelines pooled it, 249 citations in OpenAlex.

  1. Pooled it
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  3. Evidence Base Update on the Assessment of Irritability, Anger, and Aggression in Youth.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Pooled it
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  11. An Exposure-Based Cognitive-Behavioral Therapy for Youth with Severe Irritability: Feasibility and Preliminary Efficacy.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Trial
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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Denis G SukhodolskyChild Study Center, Yale University School of Medicine , New Haven, Connecticut.
Stephanie D SmithChild Study Center, Yale University School of Medicine , New Haven, Connecticut.
Spencer A McCauleyChild Study Center, Yale University School of Medicine , New Haven, Connecticut.
Karim IbrahimChild Study Center, Yale University School of Medicine , New Haven, Connecticut.
Justyna B PiaseckaChild Study Center, Yale University School of Medicine , New Haven, Connecticut.
Yale University · US

Funding

TRAINING PROGRAM IN CHILDHOOD NEUROPSYCHIATRIC DISORDERST32MH018268 · NIMH · YALE UNIVERSITY · PI Michael H Bloch, MICHAEL J CROWLEY · 1985 to 2026
$11.0M
Research Training for Medical Students & Physician-Scientists in Child PsychiatryR25MH077823 · NIMH · YALE UNIVERSITY · PI ANDRES S MARTIN · 2006 to 2026
$4.0M
Using CBT to examine circuitry of frustrative non-reward in aggressive childrenR01MH101514 · NIMH · YALE UNIVERSITY · PI PELPHREY, KEVIN A, SUKHODOLSKY, DENIS G · 2013 to 2016
$1.8M
NIMH NIH HHS R01 MH101514NIMH NIH HHS R01MH101514NIMH NIH HHS R25 MH077823NIMH NIH HHS T32 MH018268
6 · The paper itself

Abstract

objectiveAnger, irritability, and aggression are among the most common reasons for child mental health referrals. This review is focused on two forms of behavioral interventions for these behavioral problems: Parent management training (PMT) and cognitive-behavioral therapy (CBT).

methodsFirst, we provide an overview of anger/irritability and aggression as the treatment targets of behavioral interventions, followed by a discussion of the general principles and techniques of these treatment modalities. Then we discuss our current work concerning the transdiagnostic approach to CBT for anger, irritability, and aggression.

resultsPMT is aimed at improving aversive patterns of family interactions that engender children's disruptive behavior. CBT targets deficits in emotion regulation and social problem-solving that are associated with aggressive behavior. Both forms of treatment have received extensive support in randomized controlled trials. Given that anger/irritability and aggressive behavior are common in children with a variety of psychiatric diagnoses, a transdiagnostic approach to CBT for anger and aggression is described in detail.

conclusionsPMT and CBT have been well studied in randomized controlled trials in children with disruptive behavior disorders, and studies of transdiagnostic approaches to CBT for anger and aggression are currently underway. More work is needed to develop treatments for other types of aggressive behavior (e.g., relational aggression) that have been relatively neglected in clinical research. The role of callous-unemotional traits in response to behavioral interventions and treatment of irritability in children with anxiety and mood disorders also warrants further investigation.

Indexed as

AngerIrritable MoodAdolescentAggressionAttention Deficit and Disruptive Behavior DisordersChildChild Behavior DisordersCognitive Behavioral TherapyHumansParents

Identifiers

PMID26745682
PMCPMC4808268
OpenAlexW2261020264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.