Evidence map›Paper›PMID 26745452›Full record

ArticleJournal of alternative and complementary medicine (New York, N.Y.)2016

Unanticipated Insights into Biomedicine from the Study of Acupuncture.

Hugh MacPherson, Richard Hammerschlag, Remy R Coeytaux, Robert T Davis, Richard E Harris, Jiang-Ti Kong, Helene M Langevin, Lixing Lao, Ryan J Milley, Vitaly Napadow and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of alternative and complementary medicine (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
  2. Review
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  8. Review
  9. Article
  10. What Is the Point? The Problem with Acupuncture Research That No One Wants to Talk About.Journal of alternative and complementary medicine (New York, N.Y.) · 2018
    Article
  11. Spotlight on acupuncture in laboratory animal medicine.Veterinary medicine (Auckland, N.Z.) · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 13 institutions in 6 countries.

Hugh MacPherson1 Department of Health Sciences, University of York , York, United Kingdom .
Richard Hammerschlag2 Research Department, Oregon College of Oriental Medicine , Portland, OR.
Remy R Coeytaux4 Duke Clinical Research Institute , Durham, NC.
Robert T Davis6 Stromatec, Inc. , Burlington, VT.
Richard E Harris7 Department of Anesthesiology, University of Michigan , Ann Arbor, MI.
Jiang-Ti Kong8 Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine , Stanford, CA.
Helene M Langevin9 Osher Center for Integrative Medicine, Brigham and Women's Hospital and Harvard Medical School , Boston, MA.
Lixing Lao10 School of Chinese Medicine, The University of Hong Kong , Hong Kong .
Ryan J Milley2 Research Department, Oregon College of Oriental Medicine , Portland, OR.
Vitaly Napadow12 Martinos Center for Biomedical Imaging, Massachusetts General Hospital , Harvard Medical School, Charlestown, MA.
Rosa N Schnyer15 School of Nursing, University of Texas , Austin, TX.
Elisabet Stener-Victorin16 Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg , Gothenburg, Sweden .
Claudia M Witt17 Institute for Complementary and Integrative Medicine, University Hospital Zurich, University of Zurich , Zurich, Switzerland .
Peter M Wayne9 Osher Center for Integrative Medicine, Brigham and Women's Hospital and Harvard Medical School , Boston, MA.
Brigham and Women's Hospital · USClinical Research Institute · USKyung Hee University · KRMaryland University of Integrative Health · USOregon College of Oriental Medicine · USStanford University · USStromatec (United States) · USThe University of Texas at Austin · USUniversity Hospital of Zurich · CHUniversity of Gothenburg · SEUniversity of Hong Kong · HKUniversity of Michigan–Ann Arbor · USUniversity of York · GB

Funding

Interdisciplinary Research Training in Pain and Substance Use DisordersT32DA035165 · NIDA · STANFORD UNIVERSITY · PI SEAN C MACKEY · 2013 to 2026
$7.2M
Predicting Analgesic Response to Acupuncture - A Practical ApproachK23AT008477 · NCCIH · STANFORD UNIVERSITY · PI KONG, JIANG-TI · 2015 to 2019
$739k
NCCIH NIH HHS K23 AT008477NIDA NIH HHS T32 DA035165
6 · The paper itself

Abstract

Research into acupuncture has had ripple effects beyond the field of acupuncture. This paper identifies five exemplars to illustrate that there is tangible evidence of the way insights gleaned from acupuncture research have informed biomedical research, practice, or policy. The first exemplar documents how early research into acupuncture analgesia has expanded into neuroimaging research, broadening physiologic understanding and treatment of chronic pain. The second describes how the acupuncture needle has become a tool to enhance biomedical knowledge of connective tissue. The third exemplar, which illustrates use of a modified acupuncture needle as a sham device, focuses on emergent understanding of placebo effects and, in turn, on insights into therapeutic encounters in treatments unrelated to acupuncture. The fourth exemplar documents that two medical devices now in widespread use were inspired by acupuncture: transcutaneous electrical nerve stimulators for pain control and antinausea wrist bands. The final exemplar describes how pragmatic clinical trial designs applied in acupuncture research have informed current general interest in comparative effectiveness research. In conclusion, these exemplars of unanticipated outcomes of acupuncture research comprise an additional rationale for continued support of basic and clinical research evaluating acupuncture and other under-researched therapies.

Indexed as

AcupunctureAcupuncture TherapyBiomedical ResearchAcupuncture AnalgesiaChronic PainComparative Effectiveness ResearchHumansPain ManagementPlacebo EffectResearch DesignTranscutaneous Electric Nerve Stimulation

Identifiers

PMID26745452
PMCPMC4761810
OpenAlexW2227325970

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.