Rigorous Phenotyping of Cardiac iPSC Preparations Requires Knowledge of Their Resting Potential(s).

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed.

1. Characterization of Retinal VIP-Amacrine Cell Development During the Critical Period.Cellular and molecular neurobiology · 2024
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2. Whole-cell patch-clamp recording and parameters.Biophysical reviews · 2023
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3. A dynamic clamping approach using in silico IK1 current for discrimination of chamber-specific hiPSC-derived cardiomyocytes.Communications biology · 2023
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4. Human induced pluripotent stem cell-derived cardiomyocytes as an electrophysiological model: Opportunities and challenges-The Hamburg perspective.Frontiers in physiology · 2023
   Review
5. The resting membrane potential of hSC-CM in a syncytium is more hyperpolarised than that of isolated cells.Channels (Austin, Tex.) · 2021
   Article
6. ESC working group on cardiac cellular electrophysiology position paper: relevance, opportunities, and limitations of experimental models for cardiac electrophysiology research.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2021
   Review
7. A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources.The Journal of physiology · 2019
   Article
8. Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes.Stem cell reports · 2018
   Article
9. Revised roles of ISL1 in a hES cell-based model of human heart chamber specification.eLife · 2018
   Article
10. A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes.Stem cell reports · 2017
    Article
11. Switch From Fetal to AdultJournal of the American Heart Association · 2017
    Article
12. No fuzzy space for intracellular NaThe Journal of general physiology · 2017
    Article
13. Human iPSC-Derived Cardiomyocytes for Investigation of Disease Mechanisms and Therapeutic Strategies in Inherited Arrhythmia Syndromes: Strengths and Limitations.Cardiovascular drugs and therapy · 2017
    Review
14. Cardiac Subtype-Specific Modeling of KFrontiers in physiology · 2017
    Article
15. Action Potential Shape Is a Crucial Measure of Cell Type of Stem Cell-Derived Cardiocytes.Biophysical journal · 2016
    Article

Corrections and comments

• Commented on by
  The Fallacy of Assigning Chamber Specificity to iPSC Cardiac Myocytes from Action Potential Morphology.2016
• Comment on
  Action potential morphology of human induced pluripotent stem cell-derived cardiomyocytes does not predict cardiac chamber specificity and is dependent on cell density.2015

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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