Evidence map›Paper›PMID 26744578›Full record

ArticleJournal of oral biosciences2014

Life in a Diverse Oral Community - Strategies for Oxidative Stress Survival.

Leroy G Henry, Marie-Claire Boutrin, Wilson Aruni, Antonette Robles, Alexia Ximinies, Hansel M Fletcher

Open access · greenAbstract read
In one paragraph

Article in Journal of oral biosciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. TheFrontiers in cellular and infection microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Leroy G HenryDivision of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350.
Marie-Claire BoutrinDivision of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350.
Wilson AruniDivision of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350.
Antonette RoblesDivision of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350.
Alexia XiminiesDivision of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350.
Hansel M FletcherDivision of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350.
Loma Linda University · US

Funding

Studies on virulence regulation in PorphyromonasR01DE013664 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2002 to 2011
$3.3M
Mechanisms for adaptation to oxidative stress in Porphyromonas gingivalisR01DE019730 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2009 to 2013
$2.0M
ECF sigma factors in adaptation and virulence of Porphyromonas gingivalisR01DE022508 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2012 to 2016
$1.8M
Studies on the virulence of Fillifactor alocisR21DE022724 · NIDCR · LOMA LINDA UNIVERSITY · PI FLETCHER, HANSEL M. · 2012 to 2013
$427k
NIDCR NIH HHS R01 DE013664NIDCR NIH HHS R01 DE019730NIDCR NIH HHS R01 DE022508NIDCR NIH HHS R21 DE022724
6 · The paper itself

Abstract

backgroundWhile the oral cavity harbors more than 680 bacterial species, the interaction and association of selected bacterial species play a role in periodontal diseases. Bacterial species including HIGHLIGHT: In addition to novel mechanisms for oxidative resistance of individual species, community dynamics may lead to an overall strategy for survival in the inflammatory environment of the periodontal pocket. Complex systems controlled by response regulators protect against oxidative and nitrosative stress.

conclusionThe combination of these multifaceted strategies would provide a comprehensive defense and support system against the repetitive host immune response to promote microbial persistence and disease.

Indexed as

Filifactor alocisoral microbiomeoxidative stressPorphyromonas gingivalisred complex

Identifiers

PMID26744578
PMCPMC4700543
OpenAlexW2106358065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.