Evidence map›Paper›PMID 26744430›Full record

ArticleThe Journal of infectious diseases2016

Mapping Investments and Published Outputs in Norovirus Research: A Systematic Analysis of Research Funded in the United States and United Kingdom During 1997-2013.

Michael G Head, Joseph R Fitchett, Amos B Lichtman, Damilola T Soyode, Jennifer N Harris, Rifat Atun

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Norovirus in 2016-Emesis Aplenty but Clear Signs of Progress.The Journal of infectious diseases · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael G HeadFarr Institute for Health Informatics, University College London Global Health Research Institute, Faculty of Medicine, University of Southampton.
Joseph R FitchettLondon School of Hygiene and Tropical Medicine, Keppel Street, United Kingdom Harvard School of Public Health, Harvard University, Boston, Massachusetts.
Amos B LichtmanHarvard School of Public Health, Harvard University, Boston, Massachusetts.
Damilola T SoyodeHarvard School of Public Health, Harvard University, Boston, Massachusetts.
Jennifer N HarrisMRC Cancer Unit, University of Cambridge.
Rifat AtunHarvard School of Public Health, Harvard University, Boston, Massachusetts.

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundNorovirus accounts for a considerable portion of the global disease burden. Mapping national or international investments relating to norovirus research is limited.

methodsWe analyzed the focus and type of norovirus research funding awarded to institutions in the United States and United Kingdom during 1997-2013. Data were obtained from key public and philanthropic funders across both countries, and norovirus-related research was identified from study titles and abstracts. Included studies were further categorized by the type of scientific investigation, and awards related to vaccine, diagnostic, and therapeutic research were identified. Norovirus publication trends are also described using data from Scopus.

resultsIn total, US and United Kingdom funding investment for norovirus research was £97.6 million across 349 awards; 326 awards (amount, £84.9 million) were received by US institutions, and 23 awards (£12.6 million) were received by United Kingdom institutions. Combined, £81.2 million of the funding (83.2%) was for preclinical research, and £16.4 million (16.8%) was for translational science. Investments increased from £1.7 million in 1997 to £11.8 million in 2013. Publication trends showed a consistent temporal increase from 48 in 1997 to 182 in 2013.

conclusionsDespite increases over time, trends in US and United Kingdom funding for norovirus research clearly demonstrate insufficient translational research and limited investment in diagnostics, therapeutics, or vaccine research.

Indexed as

BibliometricsBiomedical ResearchCaliciviridae InfectionsGastroenteritisHumansNorovirusResearch Support as TopicUnited KingdomUnited Statesbibliometricsinfectious diseaseinvestmentsnorovirusNorwalkpolicy

Identifiers

PMID26744430
PMCPMC4704655

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.