Evidence map›Paper›PMID 26744223›Full record

ReviewTrends in genetics : TIG2016

The Floating (Pathogenicity) Island: A Genomic Dessert.

Richard P Novick, Geeta Ram

Abstract readReview
In one paragraph

Review in Trends in genetics : TIG, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 91 citations in OpenAlex.

  1. Article
  2. Article
  3. Veterinary sciences · 2025
    Review
  4. Article
  5. Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2025
    Review
  6. The group AInfection and immunity · 2025
    Article
  7. Phage Transduction of Staphylococcus aureus.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Virulence Factors in Coagulase-Negative Staphylococci.Pathogens (Basel, Switzerland) · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Richard P NovickDepartment of Medicine, Skirball Institute, New York University Medical School, New York, NY 10016, USA; Department of Microbiology, Skirball Institute, New York University Medical School, New York, NY 10016, USA. Electronic address: richard.novick@med.nyu.edu.
Geeta RamDepartment of Medicine, Skirball Institute, New York University Medical School, New York, NY 10016, USA; Department of Microbiology, Skirball Institute, New York University Medical School, New York, NY 10016, USA.
New York University · US

Funding

Molecular Biology of TSST-1 and other superantigen toxinsR01AI022159 · NIAID · PUBLIC HEALTH RESEARCH INSTITUTE · PI NOVICK, RICHARD P. · 1985 to 2014
$2.6M
NIAID NIH HHS R01 AI022159
6 · The paper itself

Abstract

Among the prokaryotic genomic islands (GIs) involved in horizontal gene transfer (HGT) are the classical pathogenicity islands, including the integrative and conjugative elements (ICEs), the gene-transfer agents (GTAs), and the staphylococcal pathogenicity islands (SaPIs), the primary focus of this review. While the ICEs and GTAs mediate HGT autonomously, the SaPIs are dependent on specific phages. The ICEs transfer primarily their own DNA, the GTAs exclusively transfer unlinked host DNA, and the SaPIs combine the capabilities of both. Thus the SaPIs derive their importance from the genes they carry (their genetic cargo) and the genes they move. They act not only as versatile high-frequency mobilizers but also as mediators of phage interference and consequently are major benefactors of their host bacteria.

Indexed as

Evolution, MolecularGene Transfer, HorizontalBacteriophagesGenomic IslandsStaphylococcushorizontal gene transfermobile genetic elementpathogenicity islandphage interferenceStaphylococcustransduction

Identifiers

PMID26744223
PMCPMC4733582
OpenAlexW2211631727

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.