ArticleWorld journal of surgical oncology2016
Value of diffusion-weighted imaging combined with conventional magnetic resonance imaging in the diagnosis of thecomas/fibrothecomas and their differential diagnosis with malignant pelvic solid tumors.
Article in World journal of surgical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 27 citations in OpenAlex.
- Magnetic resonance biomarkers in detection and characterisation of ovarian cancer: is magnetic resonance spectroscopy ready for clinical use?Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Review
- Findings on conventional ultrasonography and contrast-enhanced ultrasonography in different histopathological subtypes of ovarian thecoma-fibroma group.BMC medical imaging · 2025Article
- Diagnostic performance of a modified O-RADS classification system for adnexal lesions incorporating clinical features.Abdominal radiology (New York) · 2025Article
- Diffusion-Weighted Imaging-Based Differentiating between Benign and Malignant Ovarian Lesions.Advanced biomedical research · 2025Article
- Article
- MRI-based nomogram for differentiation of ovarian fibrothecoma and broad ligament myoma.Scientific reports · 2022Article
- The role of diffusion-weighted imaging in the evaluation of adnexal lesions.Polish journal of radiology · 2022Article
- Magnetic resonance imaging radiomics to differentiate ovarian sex cord-stromal tumors and primary epithelial ovarian cancers.Frontiers in oncology · 2022Article
- The Value of MRI Findings Combined With Texture Analysis in the Differential Diagnosis of Primary Ovarian Granulosa Cell Tumors and Ovarian Thecoma-Fibrothecoma.Frontiers in oncology · 2021Article
- MR imaging of epithelial ovarian cancer: a combined model to predict histologic subtypes.European radiology · 2020Article
- Magnetic resonance imaging of pediatric adnexal masses and mimics.Pediatric radiology · 2018Review
- MR findings of primary ovarian granulosa cell tumor with focus on the differentiation with other ovarian sex cord-stromal tumors.Journal of ovarian research · 2018Article
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8 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundOur study aims to determine the value of diffusion-weighted imaging (DWI) combined with conventional magnetic resonance imaging (MRI) in the diagnosis of thecomas/fibrothecomas and their differential diagnosis with malignant pelvic solid tumors.
methodsIn total, 36 thecomas/fibrothecomas and 40 malignant pelvic solid tumors were included in our study. All patients underwent 1.5 T conventional MRI and DWI examinations except one patient with a fibrothecoma in whom DWI examination was not performed. The clinical features and characteristics of conventional MRI and DWI of these two groups were analyzed. Apparent diffusion coefficient (ADC) values were measured and compared between groups. Univariate analysis, multivariate logistic regression analysis, and the receiver operating characteristic curve were used for statistical analysis.
resultsAll the thecomas/fibrothecomas showed isointensity on T1 weighted imaging (T1WI) and 77.8% (28/36) lesions showed hypo- to isointensity on T2 weighted imaging (T2WI). After administration of contrast medium, 94.4% (34/36) tumors appeared as minor to mild enhancement. On DWI, they showed a diversity of low to very high signal intensity. All malignant pelvic masses manifested as hyperintensity on T2WI and 87.5% (35/40) tumors showed very high signal (grade 3) on DWI. Higher area under the curve (AUC) and specificity could be achieved by using the lowest ADC value than the mean ADC value. Multivariate logistic regression analysis showed that shape, signal intensity on T2WI, capsule, and the lowest ADC value were the important indicators in discriminating thecomas/fibrothecomas from malignant pelvic solid tumors.
conclusionsThe combination of DWI and conventional MRI is of great value in the diagnosis of thecomas/fibrothecomas and their differential diagnosis with malignant pelvic solid tumors.
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