ReviewBritish journal of clinical pharmacology2016
The potential exploitation of research participants in high income countries who lack access to health care.
Review in British journal of clinical pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Practical issues in recruiting and retaining Asian American breast cancer survivors in a technology-based intervention study: A discussion paper.Journal of clinical and translational science · 2025Article
- Clinicians' experiences of obtaining informed consent for research and treatment: a nested qualitative study from Pakistan.BMC medical ethics · 2024Article
- Post-trial responsibilities in pragmatic clinical trials: Fulfilling the promise of research to drive real-world change.Learning health systems · 2024Article
- Supporting Adolescent Engagement with Artificial Intelligence-Driven Digital Health Behavior Change Interventions.Journal of medical Internet research · 2023Article
- Review
- Time for the ethical management of COVID-19 vaccines.The Lancet. Global health · 2021Review
- Minimizing Risks Is Not Enough: The Relevance of Benefits to Protecting Research Participants.Perspectives in biology and medicine · 2020Article
- The ethics of uninsured participants accessing healthcare in biomedical research: A literature review.Clinical trials (London, England) · 2018Review
- Post-trial responsibilities beyond post-trial access.Lancet (London, England) · 2018Article
- The potential exploitation of research participants in high income countries who lack access to health care.British journal of clinical pharmacology · 2016Review
- Issues in Recruiting and Retaining Asian American Breast Cancer Survivors in a Technology-Based Intervention Study.Cancer nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are millions of individuals living in North America and the European Union who lack access to healthcare services. When these individuals participate in research, they are at increased risk of being exposed to the risks and burdens of clinical trials without realizing the benefits that result from them. The mechanisms that have been proposed to ensure that research participants in low- and middle-income countries are not exploited are unlikely to protect participants in high-income countries. The present manuscript argues that one way to address concerns about exploitation in high-income countries would be to require sponsors to provide targeted benefits such as medical treatment during the trial, or the study drug after the trial. The latter could be achieved through extension studies, expanded access programs, or named-patient programs. Sponsors also might provide non-medical benefits, such as education or social support. Ethical and regulatory guidance should be revised to ensure that research participants in high-income countries who lack access to healthcare services receive sufficient benefits.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.