ArticleSurgery today2016
Clinicopathological characteristics of young patients with sporadic colorectal cancer.
Article in Surgery today, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- A comparison of overall survival from early-onset and late-onset colorectal cancer stratified by TNM stage: a systematic review.British journal of cancer · 2026Pooled it
- Comparative analysis of sporadic, IBD-associated, early-onset and late-onset colorectal cancer: a systematic review and meta-analysis.Therapeutic advances in gastroenterology · 2025Review
- Prognosis of early-onset vs. late-onset stage II/III colorectal cancer patients with adjuvant chemotherapy: a multicenter propensity score matched study.International journal of clinical oncology · 2024Article
- Comparative analysis of the clinical aspects of colorectal cancer in young adult and older adult patients in Saudi Arabia.Frontiers in oncology · 2024Article
- A Retrospective Multicenter Study of the Clinicopathological Characteristics and Prognosis of Young Adult Patients with Colorectal Cancer: Effects of Chemotherapy on Prognosis.Journal of clinical medicine · 2023Article
- Clinicopathologic characteristics of early-onset colorectal cancer.Annals of coloproctology · 2022Article
- Long-term outcomes and prognostic factors of young patients with mucinous and signet-ring cell colorectal cancer.Archives of medical science : AMS · 2020Article
- Using nomograms to predict prognostic factors in young colorectal mucinous and signet-ring cell adenocarcinoma patients.Bioscience reports · 2019Article
- Early-onset colorectal cancer in young individuals.Molecular oncology · 2019Review
- Differences in biological behaviors between young and elderly patients with colorectal cancer.PloS one · 2019Article
- The risk and survival outcome of subsequent primary colorectal cancer after the first primary colorectal cancer: cases from 1973 to 2012.BMC cancer · 2017Article
- Younger Age Is Associated with Poorer Survival in Patients with Signet-Ring Cell Carcinoma of the Colon without Distant Metastasis.Gastroenterology research and practice · 2016Article
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the clinicopathological features of and prognosis associated with sporadic colorectal cancer (CRC) in Japanese patients younger than 40 years old.
methodsThe subjects of this study were patients with sporadic stage 0-III CRC, who underwent curative resection between 2004 and 2012 at the Cancer Institute Hospital. Clinicopathological characteristics and survival were compared between the young (<40 years; n = 81) and older groups (≥40 years; n = 2257).
resultsThe median age was 36 years in the young group and 64 years in the older group. Young patients had a lower incidence of right-sided colon cancer (14 vs 28 %) and a higher incidence of rectal cancer (47 vs 32 %; P < 0.0001). The number of retrieved lymph nodes was significantly higher in the young group than in the older group (P = 0.0049). The young patients had similar overall survival and relapse-free survival to their older counterparts, except for overall survival in stage II patients (P = 0.0229). However, multivariate analysis indicated that age was not an independent prognostic factor for overall survival in patients with stage II CRC.
conclusionsYoung Japanese patients with sporadic CRC have unique characteristics such as a high incidence of rectal cancer and similar pathological features; however, they appear to have comparable survival to older patients.
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