SynthesisBMJ open2016
Progressive resistance training in Parkinson's disease: a systematic review and meta-analysis.
Synthesis in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 8 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Physical exercise and its effects on people with Parkinson's disease: Umbrella review.PloS one · 2023Pooled it
- Efficacy and evaluation of therapeutic exercises on adults with Parkinson's disease: a systematic review and network meta-analysis.BMC geriatrics · 2022Pooled it
- Effectiveness of aerobic and resistance training on the motor symptoms in Parkinson's disease: Systematic review and network meta-analysis.Frontiers in aging neuroscience · 2022Pooled it
- Effect of muscle strength training in children and adolescents with spastic cerebral palsy: A systematic review and meta-analysis.Clinical rehabilitation · 2022Pooled it
- Effects of Olympic Combat Sports on Health-Related Quality of Life in Middle-Aged and Older People: A Systematic Review.Frontiers in psychology · 2021Pooled it
- Concussion Guidelines Step 2: Evidence for Subtype Classification.Neurosurgery · 2020Guideline
- Can Resistance Training Improve Upper Limb Postural Tremor, Force Steadiness and Dexterity in Older Adults? A Systematic Review.Sports medicine (Auckland, N.Z.) · 2019Pooled it
- Systematic review on strength training in Parkinson's disease: an unsolved question.Clinical interventions in aging · 2017Pooled it
- Progressive Resistance Training in Parkinson's Disease: An Umbrella Review Examining the Role of Methodological Adherence and Training Progression Principles in Clinical Outcome.Journal of functional morphology and kinesiology · 2026Review
- Mapping motor exercise interventions in Parkinson's disease: a scoping review of intervention types, outcomes, adherence, and dropout.Frontiers in sports and active living · 2026Review
- Influence of Exercise on Oxygen Consumption, Pulmonary Ventilation, and Blood Gas Analyses in Individuals with Chronic Diseases.Life (Basel, Switzerland) · 2025Review
- General Treatments Promoting Independent Living in Parkinson's Patients and Physical Therapy Approaches for Improving Gait-A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2024Review
- Exercise-Boosted Mitochondrial Remodeling in Parkinson's Disease.Biomedicines · 2022Review
- Cognitive and Physical Intervention in Metals' Dysfunction and Neurodegeneration.Brain sciences · 2022Review
- Effects of resistance training on postural control in Parkinson's disease: a randomized controlled trial.Arquivos de neuro-psiquiatria · 2021Article
- Evidence of Rehabilitative Impact of Progressive Resistance Training (PRT) Programs in Parkinson Disease: An Umbrella Review.Parkinson's disease · 2020Review
- Exercise-induced increase in brain-derived neurotrophic factor in human Parkinson's disease: a systematic review and meta-analysis.Translational neurodegeneration · 2018Review
- Role of Physical Activity in Parkinson's Disease.Annals of Indian Academy of NeurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate if there is evidence on effectiveness of progressive resistance training in rehabilitation of Parkinson disease.
designSystematic review and meta-analysis. DATA SOURCES: Central, Medline, Embase, Cinahl, Web of Science, Pedro until May 2014. Randomised controlled or controlled clinical trials. The methodological quality of studies was assessed according to the Cochrane Collaboration's domain-based evaluation framework. DATA SYNTHESIS: random effects meta-analysis with test for heterogeneity using the I² and pooled estimate as the raw mean difference.
participantsAdults with primary/idiopathic Parkinson's disease of any severity, excluding other concurrent neurological condition.
interventionsProgressive resistance training defined as training consisting of a small number of repetitions until fatigue, allowing sufficient rest between exercises for recovery, and increasing the resistance as the ability to generate force improves. COMPARISON: Progressive resistance training versus no treatment, placebo or other treatment in randomised controlled or controlled clinical trials. PRIMARY AND SECONDARY OUTCOME MEASURES: Any outcome.
resultsOf 516 records, 12 were considered relevant. Nine of them had low risk of bias. All studies were randomised controlled trials conducted on small samples with none or 1 month follow-up after the end of intervention. Of them, six were included in quantitative analysis. Pooled effect sizes of meta-analyses on fast and comfortable walking speed, the 6 min walking test, Timed Up and Go test and maximal oxygen consumption were below the level of minimal clinical significance.
conclusionsThere is so far no evidence on the superiority of progressive resistance training compared with other physical training to support the use of this technique in rehabilitation of Parkinson's disease. SYSTEMATIC REVIEW REGISTRATION NUMBER: PROSPERO 2014:CRD42014009844.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.