ArticleBMC infectious diseases2016
Clinical features of children hospitalized with influenza A and B infections during the 2012-2013 influenza season in Italy.
Article in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical characteristics and severity of influenza infections by virus type, subtype, and lineage: A systematic literature review.Influenza and other respiratory viruses · 2018Pooled it
- Factors associated with hospitalization of people with influenza in a Malaysian tertiary hospital from 2015 to 2019.PloS one · 2025Article
- Unlocking influenza B: exploring molecular biology and reverse genetics for epidemic control and vaccine innovation.Virology journal · 2024Review
- Comparison of Clinical Presentations and Disease Severity of Children Hospitalized with Influenza A and B.Turkish archives of pediatrics · 2024Article
- Platelet distribution width as an useful indicator of influenza severity in children.BMC infectious diseases · 2024Article
- Costs and Factors Associated with Hospitalizations Due to Severe Influenza in Catalonia (2017-2020).International journal of environmental research and public health · 2022Article
- Surveying Parents' Awareness and Adherence to Influenza Vaccination Recommendations in Children in Southern Italy.Vaccines · 2022Article
- Influenza vaccination coverage in pediatric population in Italy: an analysis of recent trends.Italian journal of pediatrics · 2022Article
- Prevalence of respiratory viruses among paediatric patients in acute respiratory illnesses in Malaysia.PloS one · 2022Article
- [Health Technology Assessment (HTA) of the introduction of influenza vaccination for Italian children with Fluenz TetraJournal of preventive medicine and hygiene · 2021Article
- Clinical features and outcomes of influenza by virus type/subtype/lineage in pediatric patients.Translational pediatrics · 2021Article
- Clinical Spectrum and Burden of Influenza-Associated Neurological Complications in Hospitalised Paediatric Patients.Frontiers in pediatrics · 2021Article
- Influenza B infections in children: A review.World journal of clinical pediatrics · 2020Review
- Clinical similarities between influenza A and B in children: a single-center study, 2017/18 season, Korea.BMC pediatrics · 2019Article
- Epidemiological and clinical characteristics of children hospitalized due to influenza A and B in the south of Europe, 2010-2016.Scientific reports · 2019Article
- Influenza B virus infection complicated by life-threatening pericarditis: a unique case-report and literature review.BMC infectious diseases · 2019Review
- Single- and multiple viral respiratory infections in children: disease and management cannot be related to a specific pathogen.BMC infectious diseases · 2017Article
- A Narrative Review of Influenza: A Seasonal and Pandemic Disease.Iranian journal of medical sciences · 2017Review
- Pathogenesis and Phylogenetic Analyses of Two Avian Influenza H7N1 Viruses Isolated from Wild Birds.Frontiers in microbiology · 2016Article
- Influenza virus but not MERS coronavirus circulation in Iran, 2013-2016: Comparison between pilgrims and general population.Travel medicine and infectious diseaseArticle
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10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundInfluenza is a major public health issue worldwide. It is characterized by episodes of infection that involve hundreds of millions of people each year. Since that in the seasons 2010-2011 and 2011-2012 the circulation of FLUB was decreasing we evaluated the clinical presentation, demographic characteristics, admitting department, and length of stay in children who contracted influenza admitted to Bambino Gesù Children's Hospital, during the 2012-2013 influenza season, with the aim to establish if the recover of FLUB was associated to a clinical worsening, in comparison with those due to FLUA.
methodsA total of 133 respiratory specimens, collected from patients with symptoms of respiratory tract infections, positive for the Influenza A and B viruses (FLUA and B) were subtyped. Comparisons between the FLUA and FLUB groups were performed with the one-way ANOVA for continuous parametric variables, the Mann-Whitney test for non-parametric variables, or the Chi-Square test or Fisher's exact test (if cells <5) for categorical variables.
results87.09% of the FLUA isolates were the H1N1 subtype and 12.90% were H3N2. Among the FLUB isolates, 91.54% were the B/Yamagata/16/88 lineage and 8.45% were the B/Victoria/02/87 lineage. The largest number of FLUA/H1N1 cases was observed in children less than 1 years old, while the B/Yamagata/16/88 lineage was most prevalent in children 3-6 years old. Fever was a common symptom for both FLUA and B affected patients. However, respiratory symptoms were more prevalent in patients affected by FLUA. The median length of stay in the hospital was 5 days for FLUA and 3 days for FLUB.
conclusionsThe clinical features correlated to different Influenza viruses, and relevant subtypes, were evaluated concluding that the increasing of FLUB in the season 2012-2013 was without any dramatic change in clinical manifestation. Our findings suggest, finally, that a stronger commitment to managing patients affected by FLUA is required, as the disease is more severe than FLUB.
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