Evidence map›Paper›PMID 26743329›Full record

ArticleScientific reports2016

Development of a self-administered web-based test for longitudinal cognitive assessment.

Luis Ruano, Andreia Sousa, Milton Severo, Ivânia Alves, Márcio Colunas, Rui Barreto, Cátia Mateus, Sandra Moreira, Eduardo Conde, Virgílio Bento and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Luis RuanoDepartment of Neurology, São Sebastião Hospital, Entre Douro e Vouga Hospital Center, 4520-211 Santa Maria da Feira, Portugal.
Andreia SousaDepartment of Neurology, São Sebastião Hospital, Entre Douro e Vouga Hospital Center, 4520-211 Santa Maria da Feira, Portugal.
Milton SeveroDepartment of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto Medical School, 4200-319 Porto, Portugal.
Ivânia AlvesDepartment of Neurology, São Sebastião Hospital, Entre Douro e Vouga Hospital Center, 4520-211 Santa Maria da Feira, Portugal.
Márcio ColunasClinical Research Office, Health Sciences Department, University of Aveiro, 3810-193, Aveiro, Portugal.
Rui BarretoDepartment of Neurology, São Sebastião Hospital, Entre Douro e Vouga Hospital Center, 4520-211 Santa Maria da Feira, Portugal.
Cátia MateusDepartment of Neurology, São Sebastião Hospital, Entre Douro e Vouga Hospital Center, 4520-211 Santa Maria da Feira, Portugal.
Sandra MoreiraDepartment of Neurology, São Sebastião Hospital, Entre Douro e Vouga Hospital Center, 4520-211 Santa Maria da Feira, Portugal.
Eduardo CondeClinical Research Office, Health Sciences Department, University of Aveiro, 3810-193, Aveiro, Portugal.
Virgílio BentoUniversity Institute of Maia - ISMAI, 4475-690, Maia, Portugal.
Nuno LunetDepartment of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto Medical School, 4200-319 Porto, Portugal.
Joana PaisDepartment of Neurology, São Sebastião Hospital, Entre Douro e Vouga Hospital Center, 4520-211 Santa Maria da Feira, Portugal.
Vítor Tedim CruzDepartment of Neurology, São Sebastião Hospital, Entre Douro e Vouga Hospital Center, 4520-211 Santa Maria da Feira, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sequential testing with brief cognitive tools has been recommended to improve cognitive screening and monitoring, however the few available tools still depend on an external evaluator and periodic visits. We developed a self-administered computerized test intended for longitudinal cognitive testing (Brain on Track). The test can be performed from a home computer and is composed of several subtests, expected to evaluate different cognitive domains, all including random elements to minimize learning effects. An initial (A) and a refined version of the test (B) were applied to patients with mild cognitive impairment or early dementia (n = 88) and age and education-matched controls. A subsample of a population-based cohort (n = 113) performed the test at home every three months to evaluate test-retest reliability. The test's final version Cronbach's alpha was 0.90, test scores were significantly different between patients and controls (p = 0.001), the area under the receiver operating characteristic curve was 0.75 and the smallest real difference (43.04) was lower than the clinical relevant difference (56.82). In the test-retest reliability analysis 9/10 subtests showed two-way mixed single intraclass consistency correlation coefficient >0.70. These results imply good internal consistency, discriminative ability and reliability when performed at home, encouraging further longitudinal clinical and population-based studies.

Indexed as

AgedAged, 80 and overCognitionCognitive DysfunctionDementiaEducational StatusFemaleHumansInternetMaleMiddle AgedNeuropsychological TestsPrincipal Component AnalysisPsychometricsReproducibility of ResultsResearch Design

Identifiers

PMID26743329
PMCPMC4705487

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.