Evidence map›Paper›PMID 26743326›Full record

SynthesisArchives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists2016

Examination of Variables That May Affect the Relationship Between Cognition and Functional Status in Individuals with Mild Cognitive Impairment: A Meta-Analysis.

Courtney Mcalister, Maureen Schmitter-Edgecombe, Richard Lamb

Abstract readMeta-Analysis
In one paragraph

Synthesis in Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Prescribing Assistive Technology for Cognition to Support Aging in Place: OTs' Perspective.Canadian journal of occupational therapy. Revue canadienne d'ergotherapie · 2026
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  6. Everyday functioning in treatment-resistant late-life depression: The mediating role of cognition.Journal of the International Neuropsychological Society : JINS · 2025
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  16. Decreased 5-HTSynapse (New York, N.Y.) · 2022
    Article
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  20. The night out task and scoring application: an ill-structured, open-ended clinic-based test representing cognitive capacities used in everyday situations.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Courtney McalisterDepartment of Psychology, Washington State University, Pullman, WA, USA.
Maureen Schmitter-EdgecombeDepartment of Psychology, Washington State University, Pullman, WA, USA schmitter-e@wsu.edu.
Richard LambDepartment of Teaching and Learning, Washington State University, Pullman, WA, USA.

Funding

Multidisciplinary undergraduate training program in Health-assistive Smart EnvironmentsR25AG046114 · NIA · WASHINGTON STATE UNIVERSITY · PI COOK, DIANE JOYCE, MINOR, BRYAN · 2014 to 2025
$3.4M
Smart Technologies for Health Assessment and AssistanceR01EB009675 · NIBIB · WASHINGTON STATE UNIVERSITY · PI COOK, DIANE JOYCE, SCHMITTER-EDGECOMBE, MAUREEN · 2010 to 2017
$2.6M
Smart environment technology for longitudinal behavior analysis and interventionR01EB015853 · NIBIB · WASHINGTON STATE UNIVERSITY · PI COOK, DIANE JOYCE, SCHMITTER-EDGECOMBE, MAUREEN · 2012 to 2015
$1.5M
NIA NIH HHS R25 AG046114NIBIB NIH HHS R01 EB009675NIBIB NIH HHS R01 EB015853
6 · The paper itself

Abstract

The objective of this meta-analysis was to improve understanding of the heterogeneity in the relationship between cognition and functional status in individuals with mild cognitive impairment (MCI). Demographic, clinical, and methodological moderators were examined. Cognition explained an average of 23% of the variance in functional outcomes. Executive function measures explained the largest amount of variance (37%), whereas global cognitive status and processing speed measures explained the least (20%). Short- and long-delayed memory measures accounted for more variance (35% and 31%) than immediate memory measures (18%), and the relationship between cognition and functional outcomes was stronger when assessed with informant-report (28%) compared with self-report (21%). Demographics, sample characteristics, and type of everyday functioning measures (i.e., questionnaire, performance-based) explained relatively little variance compared with cognition. Executive functioning, particularly measured by Trails B, was a strong predictor of everyday functioning in individuals with MCI. A large proportion of variance remained unexplained by cognition.

Indexed as

Activities of Daily LivingCognitionAgingCognitive DysfunctionExecutive FunctionHumansMemoryNeuropsychological TestsSelf ReportAgingCognitionExecutive functionMemoryMeta-Analysis

Identifiers

PMID26743326
PMCPMC4758380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.