Evidence map›Paper›PMID 26743050›Full record

ReviewDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete2016

[Intrinsic factors, genes, and skin aging].

E Makrantonaki, G P Pfeifer, C C Zouboulis

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

E MakrantonakiKlinik für Dermatologie und Allergologie, Universitätsklinikum Ulm, Albert-Einstein Allee 23, Life Sciences Building N27, James-Franck Ring/ Meyerhofstr. 11c, 89081, Ulm, Deutschland.
G P PfeiferCenter for Epigenetics, Van Andel Research Institute, 333 Bostwick Avenue NE, 49503, Grand Rapids, MI, USA.
C C ZouboulisKlinik für Dermatologie, Venerologie und Allergologie, Immunologisches Zentrum, Städtisches Klinikum Dessau, Auenweg 38, 06487, Dessau, Deutschland. christos.zouboulis@klinikum-dessau.de.
Städtisches Klinikum Dessau · DEUniversity Hospital Ulm · DEVan Andel Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin aging is determined by a combination of endogenous and environmental influences, including epigenetic, posttranslational, microbial, and lifestyle factors. In particular genetic changes, programmed or not, play a pivotal role and understanding of these complex mechanisms may contribute to the prevention of age-related diseases and extension of healthy lifespan. In this article, new knowledge about genes and biological processes that can significantly affect skin homeostasis in old age and can lead to the typical morphological and physiological characteristics of aging skin are summarized.

Indexed as

AgingAnimalsEpigenesis, GeneticGene Expression Regulation, DevelopmentalGenetic Predisposition to DiseaseHumansLongevityModels, GeneticSkin AgingEpigeneticsGene expressionGeneticsMutationsSkin homeostasis

Identifiers

PMID26743050
OpenAlexW2226036067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.