Evidence map›Paper›PMID 26743043›Full record

ReviewNeurobiology of learning and memory2016

Getting directions from the hippocampus: The neural connection between looking and memory.

Miriam L R Meister, Elizabeth A Buffalo

Abstract readReview
In one paragraph

Review in Neurobiology of learning and memory, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Article
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  3. Article
  4. Review
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  8. Decoding memory function through naturalistic gaze patterns.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
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  15. Article
  16. Spontaneous eye movements reflect the representational geometries of conceptual spaces.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Do microsaccades vary with discriminability around the visual field?bioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Dynamic interactions between memory and viewing behaviors: Insights from dyadic modeling of eye movements.Journal of experimental psychology. Human perception and performance · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Miriam L R MeisterDepartment of Physiology and Biophysics, University of Washington, USA; Washington National Primate Research Center, USA; University of Washington School of Medicine, USA.
Elizabeth A BuffaloDepartment of Physiology and Biophysics, University of Washington, USA; Washington National Primate Research Center, USA; University of Washington School of Medicine, USA.

Funding

Washington National Primate Research CenterP51OD010425 · OD · UNIVERSITY OF WASHINGTON · PI Mari Ostendorf · 2012 to 2026
$201.8M
Neuronal Synchronization in the Medial Temporal Lobe and Memory FormationR01MH080007 · NIMH · UNIVERSITY OF WASHINGTON · PI BUFFALO, ELIZABETH A · 2008 to 2018
$4.7M
The Neural Basis of Relational MemoryR01MH093807 · NIMH · UNIVERSITY OF WASHINGTON · PI BUFFALO, ELIZABETH A · 2012 to 2016
$2.6M
NIH HHS P51 OD010425NIMH NIH HHS R01 MH080007NIMH NIH HHS R01 MH093807
6 · The paper itself

Abstract

Investigations into the neural basis of memory in human and non-human primates have focused on the hippocampus and associated medial temporal lobe (MTL) structures. However, how memory signals from the hippocampus affect motor actions is unknown. We propose that approaching this question through eye movement, especially by assessing the changes in looking behavior that occur with experience, is a promising method for exposing neural computations within the hippocampus. Here, we review how looking behavior is guided by memory in several ways, some of which have been shown to depend on the hippocampus, and how hippocampal neural signals are modulated by eye movements. Taken together, these findings highlight the need for future research on how MTL structures interact with the oculomotor system. Probing how the hippocampus reflects and impacts motor output during looking behavior renders a practical path to advance our understanding of the hippocampal memory system.

Indexed as

AnimalsEye MovementsHippocampusHumansMemoryTemporal LobeVisual PerceptionEye movementsFree-viewingHippocampusMedial temporal lobeMemoryNeuronsPrimateSaccades

Identifiers

PMID26743043
PMCPMC4927424

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.