Evidence map›Paper›PMID 26742756›Full record

ArticleClinical rheumatology2016

Arterial stiffness is associated with left ventricular dysfunction in patients with rheumatoid arthritis.

Abdulselam Ilter, Abdulkadir Kiris, Murat Karkucak, Mursel Sahin, Omer Faruk Serdar, Yunus Ugan

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Abdulselam IlterDepartments of Cardiology, Sanliurfa Mehmet Akif Inan Training and Research Hospital, Sanliurfa, Turkey. abdulselamilter@gmail.com.
Abdulkadir KirisDepartments of Cardiology, Faculty of Medicine, Farabi Hospital, Karadeniz Technical University, Trabzon, Turkey.
Murat KarkucakDepartments of Physical Medicine and Rehabilitation, Division of Rheumatology, Faculty of Medicine, Farabi Hospital, Karadeniz Technical University, Trabzon, Turkey.
Mursel SahinDepartments of Cardiology, Ahi Evren Thoracic and Cardiovascular Surgery Training and Research Hospital, Trabzon, Turkey.
Omer Faruk SerdarDepartments of Physical Medicine and Rehabilitation, Division of Rheumatology, Faculty of Medicine, Farabi Hospital, Karadeniz Technical University, Trabzon, Turkey.
Yunus UganDepartments of Internal Medicine, Division of Rheumatology, Sanliurfa Mehmet Akif Inan Training and Research Hospital, Sanliurfa, Turkey.
Karadeniz Technical University · TRŞanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi · TRMinistry of Health · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arterial stiffness (AS) has a detrimental effect on cardiovascular system particularly on left ventricle (LV). The aim of the study was to evaluate the impact of AS on LV functions in patients with rheumatoid arthritis (RA). Forty patients with RA and 25 age-sex matched control subjects (mean age 48.5 ± 6.3 vs. 45.1 ± 6.9 years, respectively, p = 0.06) were enrolled in study. AS was assessed by carotid-femoral pulse wave velocity (CF-PWV) and heart rate corrected augmentation index (AIx@75) measured by applanation tonometry (SphygmoCor). LV function was evaluated using tissue Doppler-derived myocardial performance index (MPI) from lateral mitral annulus. CF-PWV (28.3 ± 10.3 vs. 21.8 ± 9.3 m/s, p = 0.03), AIx@75 (10.2 ± 2.3 vs. 9.2 ± 1, %, p = 0.01) and MPI (0.46 ± 0.12 vs. 0.36 ± 0.1, p < 0.001) were significantly higher in patients with RA than in controls. LV MPI was found to be significantly positive correlated with CF-PWV, AIx@75, and ESR (r = 0.360, p = 0.005; r = 0.334, p = 0.009; r = 0.293, p = 0.023, respectively). Arterial stiffness parameters including CF-PWV and AIx@75 are associated with subclinical left ventricular dysfunction in patients with RA.

Indexed as

AdultArthritis, RheumatoidBlood Flow VelocityEchocardiography, DopplerFemaleHumansMaleMiddle AgedPulse Wave AnalysisVascular StiffnessVentricular Dysfunction, LeftArterial stiffnessAugmentation indexHeart failureMyocardial performance indexPulse wave velocityRheumatoid arthritis

Identifiers

PMID26742756
OpenAlexW2226732771

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.