Evidence map›Paper›PMID 26742527›Full record

ArticleMolecular neurobiology2017

lncRNA NONRATT021972 siRNA Decreases Diabetic Neuropathic Pain Mediated by the P2X

Haiying Peng, Lifang Zou, Jinyan Xie, Hong Wu, Bing Wu, Gaochun Zhu, Qiulan Lv, Xi Zhang, Shuangmei Liu, Guilin Li and 7 more

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Galectin-related protein, a key contributor, drives diabetes-associated neuropathic pain.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Diabetic neuropathy: cutting-edge research and future directions.Signal transduction and targeted therapy · 2025
    Review
  4. Review
  5. Oligonucleotide therapies for nonalcoholic steatohepatitis.Molecular therapy. Nucleic acids · 2024
    Review
  6. Review
  7. Metabolic memory: mechanisms and diseases.Signal transduction and targeted therapy · 2024
    Review
  8. Review
  9. Review
  10. Review
  11. Peripheral mechanisms of peripheral neuropathic pain.Frontiers in molecular neuroscience · 2023
    Review
  12. LncRNA-UC.25 + shRNA Alleviates P2YMolecular neurobiology · 2022
    Article
  13. Review
  14. Ion channel long non-coding RNAs in neuropathic pain.Pflugers Archiv : European journal of physiology · 2022
    Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Haiying PengDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Lifang ZouDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Jinyan XieDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Hong WuDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Bing WuDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Gaochun ZhuDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Qiulan LvDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Xi ZhangDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Shuangmei LiuDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Guilin LiDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Hong XuDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Yun GaoDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Changshui XuDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Chunping ZhangDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Shouyu WangDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Yun XueDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Shangdong LiangDepartment of Physiology, Medical College of Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China. liangsd@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) participate in physiological and pathophysiological processes. Type 2 diabetes mellitus (T2DM) accounts for more than 90 % of all cases of diabetes mellitus (DM). Diabetic neuropathic pain (DNP) is a common complication of T2DM. The aim of this study was to investigate the effects of lncRNA NONRATT021972 small interference RNA (siRNA) on DNP mediated by the P2X

Indexed as

AnimalsDiabetes Mellitus, Type 2Diabetic NeuropathiesGanglia, SpinalHumansMaleNeuralgiaRatsRats, Sprague-DawleyReceptors, Purinergic P2X3RNA, Long NoncodingRNA, Small Interferinglong non-coding RNA NONRATT021972, ratReceptors, Purinergic P2X3RNA, Long NoncodingRNA, Small InterferingDiabetic neuropathic painDorsal root gangliaLong noncoding RNAP2X3 receptor

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.