Evidence map›Paper›PMID 26742105›Full record

ReviewPLoS pathogens2016

SOD Enzymes and Microbial Pathogens: Surviving the Oxidative Storm of Infection.

Chynna N Broxton, Valeria C Culotta

Abstract readReview
In one paragraph

Review in PLoS pathogens, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Drug-resistantClinical microbiology reviews · 2025
    Pooled it
  2. Cascading damage toProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Antioxidant Activity of EthanolicMolecules (Basel, Switzerland) · 2026
    Article
  5. TheJournal of fungi (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Article
  8. Understanding Iron and Oxidative Stress Response inbioRxiv : the preprint server for biology · 2026
    Article
  9. From hemocuprein to CSRP: the many faces of Cu/Zn superoxide dismutase.Metallomics : integrated biometal science · 2026
    Review
  10. A roadmap to chemically reactive species: how diverse oxidants affectMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  11. Article
  12. Hemocyanin controlsVirulence · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Journal of fungi (Basel, Switzerland) · 2025
    Article
  18. Functional Analysis ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  19. Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chynna N BroxtonDepartment of Biochemistry and Molecular Biology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
Valeria C CulottaDepartment of Biochemistry and Molecular Biology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

Funding

TRAINING IN AREAS FUNDAMENTAL TO CANCER RESEARCHT32CA009110 · NCI · JOHNS HOPKINS UNIVERSITY · PI MATUNIS, MICHAEL J., WEERARATNA, ASHANI T · 1985 to 2025
$13.1M
Genetic Determinants of Oxygen ToxicityR37GM050016 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI CULOTTA, VALERIA C · 2005 to 2014
$3.6M
GENETIC DETERMINANTS OF OXYGEN TOXICITYR01GM050016 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI CULOTTA, VALERIA C · 1993 to 2018
$3.0M
Copper as a nutrient for Candida albicans at the host-pathogen interfaceR01AI119949 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CULOTTA, VALERIA C · 2015 to 2019
$2.3M
Superoxide dismutases and mitochondrial oxidative stress in Candida albicans.F31GM113637 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI BROXTON, CHYNNA · 2015 to 2016
$87k
NCI NIH HHS T32 CA009110NIAID NIH HHS R01 AI119949NIGMS NIH HHS F31 GM113637NIGMS NIH HHS R01 GM050016NIGMS NIH HHS R37 GM050016NIGMS NIH HHS R37 GM50016
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsHost-Pathogen InteractionsHumansOxidative StressSuperoxide DismutaseSuperoxide Dismutase

Identifiers

PMID26742105
PMCPMC4712152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.