Evidence map›Paper›PMID 26742099›Full record

ArticlePloS one2016

Development of a Larvicidal Nanoemulsion with Pterodon emarginatus Vogel Oil.

Anna E M F M Oliveira, Jonatas L Duarte, Jesus R R Amado, Rodrigo A S Cruz, Clarice F Rocha, Raimundo N P Souto, Ricardo M A Ferreira, Karen Santos, Edemilson C da Conceição, Leandra A R de Oliveira and 3 more

Abstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Targeting the vector of arbovirusesBeilstein journal of nanotechnology · 2025
    Review
  5. Article
  6. Complete Chloroplast Genomes ofCurrent genomics · 2023
    Article
  7. Article
  8. Larvicidal Effect ofMolecules (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Recent progress in micro and nano-encapsulation of bioactive derivatives of the Brazilian genus Pterodon.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Review
  11. Review
  12. Article
  13. Review
  14. Botanical insecticide-based nanosystems for the control of Aedes (Stegomyia) aegypti larvae.Environmental science and pollution research international · 2020
    Review
  15. Plant Natural Products for the Control ofMolecules (Basel, Switzerland) · 2020
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Nanoemulsion of Dill essential oil as a green and potent larvicide against Anopheles stephensi.Environmental science and pollution research international · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anna E M F M OliveiraLaboratório de Pesquisa em Fármacos, Colegiado de Farmácia, Universidade Federal do Amapá, Campus Universitário Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02 Bairro Zerão, CEP: 68902-280, Macapá, AP, Brazil.
Jonatas L DuarteLaboratório de Pesquisa em Fármacos, Colegiado de Farmácia, Universidade Federal do Amapá, Campus Universitário Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02 Bairro Zerão, CEP: 68902-280, Macapá, AP, Brazil.
Jesus R R AmadoLaboratório de Pesquisa em Fármacos, Colegiado de Farmácia, Universidade Federal do Amapá, Campus Universitário Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02 Bairro Zerão, CEP: 68902-280, Macapá, AP, Brazil.
Rodrigo A S CruzLaboratório de Pesquisa em Fármacos, Colegiado de Farmácia, Universidade Federal do Amapá, Campus Universitário Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02 Bairro Zerão, CEP: 68902-280, Macapá, AP, Brazil.
Clarice F RochaLaboratório de Pesquisa em Fármacos, Colegiado de Farmácia, Universidade Federal do Amapá, Campus Universitário Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02 Bairro Zerão, CEP: 68902-280, Macapá, AP, Brazil.
Raimundo N P SoutoLaboratório de Artrópodes, Universidade Federal do Amapá, Colegiado de Ciências Biológicas, Universidade Federal do Amapá, Campus Universitário Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02 Bairro Zerão, CEP: 68902-280, Macapá, AP, Brazil.
Ricardo M A FerreiraLaboratório de Artrópodes, Universidade Federal do Amapá, Colegiado de Ciências Biológicas, Universidade Federal do Amapá, Campus Universitário Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02 Bairro Zerão, CEP: 68902-280, Macapá, AP, Brazil.
Karen SantosLaboratório de Artrópodes, Universidade Federal do Amapá, Colegiado de Ciências Biológicas, Universidade Federal do Amapá, Campus Universitário Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02 Bairro Zerão, CEP: 68902-280, Macapá, AP, Brazil.
Edemilson C da ConceiçãoLaboratório de Pesquisa, Desenvolvimento e Inovação em Bioprodutos, Universidade Federal de Goiás, Faculdade de Farmácia, Praça Universitária, 1166, Setor Leste Universitário Universitário, CEP: 74605220, Goiânia, GO, Brazil.
Leandra A R de OliveiraLaboratório de Pesquisa, Desenvolvimento e Inovação em Bioprodutos, Universidade Federal de Goiás, Faculdade de Farmácia, Praça Universitária, 1166, Setor Leste Universitário Universitário, CEP: 74605220, Goiânia, GO, Brazil.
Alphonse KelecomLaboratório de Produtos Naturais do Mar e de Química Bio-Orgânica, Universidade Federal Fluminense, Instituto de Biologia, Outeiro de São João Batista s/n, CEP: 24001970, Niterói, RJ, Brazil.
Caio P FernandesLaboratório de Pesquisa em Fármacos, Colegiado de Farmácia, Universidade Federal do Amapá, Campus Universitário Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02 Bairro Zerão, CEP: 68902-280, Macapá, AP, Brazil.
José C T CarvalhoLaboratório de Pesquisa em Fármacos, Colegiado de Farmácia, Universidade Federal do Amapá, Campus Universitário Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02 Bairro Zerão, CEP: 68902-280, Macapá, AP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pterodon emarginatus Vogel is a Brazilian species that belongs to the family Fabaceae, popularly known as sucupira. Its oil has several biological activities, including potent larvicidal property against Aedes aegypti. This insect is the vector of dengue, a tropical disease that has been considered a critical health problem in developing countries, such as Brazil. Most of dengue control methods involve larvicidal agents suspended or diluted in water and making active lipophilic natural products available is therefore considered a technological challenge. In this context, nanoemulsions appear as viable alternatives to solve this major problem. The present study describes the development of a novel nanoemulsion with larvicidal activity against A. aegypti along with the required Hydrophile Lipophile Balance determination of this oil. It was suggested that the mechanism of action might involve reversible inhibition of acetylcholinesterase and our results also suggest that the P. emarginatus nanoemulsion is not toxic for mammals. Thus, it contributes significantly to alternative integrative practices of dengue control, as well as to develop sucupira based nanoproducts for application in aqueous media.

Indexed as

AcetylcholinesteraseAedesAnimalsBehavior, AnimalDengueEmulsionsFabaceaeFemaleHydrophobic and Hydrophilic InteractionsInsecticidesInsect ProteinsLarvaLethal Dose 50MiceMosquito ControlNanostructuresAcetylcholinesteraseEmulsionsInsecticidesInsect ProteinsOils, VolatilePlant Extracts

Identifiers

PMID26742099
PMCPMC4711774

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.