Trial reportNutrients2016
Maternal Nutrition and Glycaemic Index during Pregnancy Impacts on Offspring Adiposity at 6 Months of Age--Analysis from the ROLO Randomised Controlled Trial.
Trial report in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 6 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Addressing obesity in the first 1000 days in high risk infants: Systematic review.Maternal & child nutrition · 2021Pooled it
- Pooled it
- Associations between lifestyle interventions during pregnancy and childhood weight and growth: a systematic review and meta-analysis.The international journal of behavioral nutrition and physical activity · 2021Pooled it
- Health professional-delivered obesity prevention interventions during the first 1,000 days: A systematic review of external validity reporting.HRB open research · 2019Pooled it
- Can antenatal diet and lifestyle interventions influence childhood obesity? A systematic review.Maternal & child nutrition · 2018Pooled it
- Animal models of maternal high fat diet exposure and effects on metabolism in offspring: a meta-regression analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2017Pooled it
- Low glycaemic index diet in pregnancy and child asthma: follow-up of the ROLO trial.The British journal of nutrition · 2026Trial
- Cardiovascular fitness is associated with child adiposity at 5 years of age: findings from the ROLO longitudinal birth cohort study.BMC pediatrics · 2023Trial
- Trial
- The effect of high dietary fiber intake on gestational weight gain, fat accrual, and postpartum weight retention: a randomized clinical trial.BMC pregnancy and childbirth · 2020Trial
- Effects of an antenatal dietary intervention in overweight and obese women on 6 month infant outcomes: follow-up from the LIMIT randomised trial.International journal of obesity (2005) · 2018Trial
- Infant adiposity following a randomised controlled trial of a behavioural intervention in obese pregnancy.International journal of obesity (2005) · 2017Trial
- Resting Metabolic Rate Rises in Pregnancy, but Energy Intake and Active Expenditure Remain Stable: A Pilot Study.The Australian & New Zealand journal of obstetrics & gynaecology · 2026Article
- Respiratory Quotient During Pregnancy and the Influence of Macronutrient Intake, Energy Balance and Maternal Fat Mass: An Exploratory Study.The Australian & New Zealand journal of obstetrics & gynaecology · 2026Article
- Higher prenatal dietary glycemic index in the third trimester of pregnancy is associated with infant negative affect at 6 months.Scientific reports · 2025Article
- Macrosomia and Childhood Growth Trajectories From Birth to 10 Years of Age: Findings From the ROLO Longitudinal Birth Cohort Study.Journal of obesity · 2025Article
- Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening.Diagnostics (Basel, Switzerland) · 2023Review
- Underreporting of Energy Intake Increases over Pregnancy: An Intensive Longitudinal Study of Women with Overweight and Obesity.Nutrients · 2022Article
- Associations between the Maternal Exposome and Metabolome during Pregnancy.Environmental health perspectives · 2022Article
- Maternal Dietary Quality and Dietary Inflammation Associations with Offspring Growth, Placental Development, and DNA Methylation.Nutrients · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood obesity is associated with increased risk of adult obesity and metabolic disease. Diet and lifestyle in pregnancy influence fetal programming; however the influence of specific dietary components, including low glycaemic index (GI), remains complex. We examined the effect of a maternal low GI dietary intervention on offspring adiposity at 6 months and explored the association between diet and lifestyle factors in pregnancy and infant body composition at 6 months. 280 6-month old infant and mother pairs from the control (n = 142) and intervention group (n = 138), who received low GI dietary advice in pregnancy, in the ROLO study were analysed. Questionnaires (food diaries and lifestyle) were completed during pregnancy, followed by maternal lifestyle and infant feeding questionnaires at 6 months postpartum. Maternal anthropometry was measured throughout pregnancy and at 6 months post-delivery, along with infant anthropometry. No difference was found in 6 months infant adiposity between control and intervention groups. Maternal trimester three GI, trimester two saturated fats and trimester one and three sodium intake were positively associated with offspring adiposity, while trimester two and three vitamin C intake was negatively associated. In conclusion associations were observed between maternal dietary intake and GI during pregnancy and offspring adiposity at 6 months of age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.