Evidence map›Paper›PMID 26742025›Full record

ArticleMolecules (Basel, Switzerland)2016

Evaluation of the Nano-TiO2 as a Novel Deswelling Material.

Ming Chu, Yue-Long Hou, Lan Xu, Zheng-Yun Chu, Ming-Bo Zhang, Yue-Dan Wang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ming ChuDepartment of Immunology, School of Basic Medical Sciences, Peking University, Beijing 100191, China. famous@bjmu.edu.cn.
Yue-Long HouDepartment of Immunology, School of Basic Medical Sciences, Peking University, Beijing 100191, China. hou.yuelong@163.com.
Lan XuDepartment of Immunology, School of Basic Medical Sciences, Peking University, Beijing 100191, China. xulanyn@163.com.
Zheng-Yun ChuPharmacy Department, Liao Ning University of Traditional Chinese Medicine, Shenyang 116600, Liao Ning, China. chuzhengyun@163.com.
Ming-Bo ZhangPharmacy Department, Liao Ning University of Traditional Chinese Medicine, Shenyang 116600, Liao Ning, China. mbzhang@126.com.
Yue-Dan WangDepartment of Immunology, School of Basic Medical Sciences, Peking University, Beijing 100191, China. yff1118@163.com.
Peking University · CNLiaoning University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nano-TiO2 is widely applied in the automobile exhaust hose reels as a catalyst to reduce oxynitride emissions, including nitric oxide (NO). In the biomedicine field, NO plays an important role in vasodilation and edema formation in human bodies. However, the deswelling activity of nano-TiO2 has not been reported. Here, we demonstrated that nano-TiO2 can significantly degrade the production of NO in LPS-induced RAW264.7 mouse macrophages. Further study indicated that nano-TiO2 exhibited an effect on vascular permeability inhibition, and prevented carrageenan-induced footpad edema. Therefore, we prepared a nano-TiO2 ointment and observed similar deswelling effects. In conclusion, nano-TiO2 might act as a novel deswelling agent related with its degradation of NO, which will aid in our ability to design effective interventions for edema involved diseases.

Indexed as

AnimalsAnti-Inflammatory Agents, Non-SteroidalCapillary PermeabilityCarrageenanCatalysisCell LineEdemaFemaleHindlimbMacrophagesMiceNanostructuresNitric OxideRatsRats, Sprague-DawleyTitaniumAnti-Inflammatory Agents, Non-SteroidalCarrageenanNitric OxideTitaniumtitanium dioxidedeswelling activitynano-TiO2nano-TiO2 ointmentnitric oxidevascular permeability

Identifiers

PMID26742025
PMCPMC6272895
OpenAlexW2223388600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.