Evidence map›Paper›PMID 26741576›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2016

Comparison of non-invasive vs invasive blood pressure measurement in neonates undergoing therapeutic hypothermia for hypoxic ischemic encephalopathy.

J Zhou, O Elkhateeb, K-S Lee

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

J ZhouDivision of Neonatology, Hospital for Sick Children, Toronto, ON, Canada.
O ElkhateebDivision of Neonatology, Hospital for Sick Children, Toronto, ON, Canada.
K-S LeeDivision of Neonatology, Hospital for Sick Children, Toronto, ON, Canada.
Hospital for Sick Children · CAChildren's Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the accuracy of blood pressure (BP) measured non-invasively (NIBP) compared with invasive arterial BP (IABP) measured by umbilical arterial catheter in neonates undergoing therapeutic hypothermia (TH) for hypoxic ischemic encephalopathy (HIE). STUDY

designWe conducted a retrospective study of neonates with gestational age (GA)⩾35 weeks with HIE who received TH. Paired NIBP and IABP measurements were obtained during TH and during normothermia.

resultWe collected 897 paired measurements from 40 infants, which included 623 pairs during TH and 274 pairs during normothermia. The mean±s.d. differences in BP measured by NIBP compared with IABP in mmHg were -0.2±8.8 (P=0.505) for systolic BP (SBP), -4.5±8.3 (P<0.001) for diastolic BP (DBP) and -5.1±7.5 (P<0.001) for mean BP (MBP) during TH; and -1.3±9.2 (P=0.016) for SBP, -7.5±7.8 (P<0.001) for DBP and -7.3±6.8 (P<0.001) for MBP during normothermia. Overall 466/623 (74.8%), 324/623 (52.0%) and 363/623 (58.3%) of NIBP measurements of SBP, DBP and MBP, respectively, were clinically acceptable (defined as difference ⩽15% of IABP reading) during TH; and 202/274 (73.7%), 118/274 (43.1%) and 148/274 (54.0%), were clinically acceptable during normothermia.

conclusionIn term or near-term neonates with HIE, NIBP measurements are a robust method to determine SBP; however, DBP and MBP are underestimated. Determination of hypotension using the MBP measured non-invasively should be interpreted with caution.

Indexed as

Catheterization, PeripheralArterial PressureBlood Pressure DeterminationFemaleHumansHypothermia, InducedHypoxia-Ischemia, BrainInfant, NewbornMaleMonitoring, PhysiologicPostnatal CareReproducibility of ResultsRetrospective StudiesUmbilical Arteries

Identifiers

PMID26741576
OpenAlexW2231524025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.