Evidence map›Paper›PMID 26741344›Full record

ArticlePhysics in medicine and biology2016

Analytical estimation of ultrasound properties, thermal diffusivity, and perfusion using magnetic resonance-guided focused ultrasound temperature data.

C R Dillon, G Borasi, A Payne

Abstract readEvaluation Study
In one paragraph

Article in Physics in medicine and biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Evaluation of acoustic-thermal simulations of in vivo magnetic resonance guided focused ultrasound ablative therapy.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2024
    Article
  2. Experimental validation of acoustic and thermal modeling in heterogeneous phantoms using the hybrid angular spectrum method.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2021
    Article
  3. Article
  4. Validation of hybrid angular spectrum acoustic and thermal modelling in phantoms.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2018
    Article
  5. Development and validation of a MRgHIFU non-invasive tissue acoustic property estimation technique.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2016
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

C R DillonDepartment of Radiology, University of Utah, 729 Arapeen Dr, Salt Lake City, UT 84108, USA.
G BorasiInstitute for Bioimaging and Molecular Physiology, National Research Council, Via F.lli Cervi, 93 - 20090 Segrate (MI), Italy.
A PayneDepartment of Radiology, University of Utah, 729 Arapeen Dr, Salt Lake City, UT 84108, USA.

Funding

Non-Invasive MRI-Guided HIFU for Breast Cancer TherapyR01CA172787 · NCI · UNIVERSITY OF UTAH · PI PARKER, DENNIS L · 2013 to 2017
$2.7M
Improved MRI temperature imaging using a subject-specific biophysical modelR01EB013433 · NIBIB · UNIVERSITY OF UTAH · PI PARKER, DENNIS L · 2011 to 2014
$1.8M
The role of T2 and blood flow properties in MRgFUS treatments of uterine fibroidsF32HD085685 · NICHD · UNIVERSITY OF UTAH · PI DILLON, CHRISTOPHER R · 2015 to 2017
$137k
NCI NIH HHS R01 CA172787NIBIB NIH HHS R01 EB013433NICHD NIH HHS F32 HD085685
6 · The paper itself

Abstract

For thermal modeling to play a significant role in treatment planning, monitoring, and control of magnetic resonance-guided focused ultrasound (MRgFUS) thermal therapies, accurate knowledge of ultrasound and thermal properties is essential. This study develops a new analytical solution for the temperature change observed in MRgFUS which can be used with experimental MR temperature data to provide estimates of the ultrasound initial heating rate, Gaussian beam variance, tissue thermal diffusivity, and Pennes perfusion parameter. Simulations demonstrate that this technique provides accurate and robust property estimates that are independent of the beam size, thermal diffusivity, and perfusion levels in the presence of realistic MR noise. The technique is also demonstrated in vivo using MRgFUS heating data in rabbit back muscle. Errors in property estimates are kept less than 5% by applying a third order Taylor series approximation of the perfusion term and ensuring the ratio of the fitting time (the duration of experimental data utilized for optimization) to the perfusion time constant remains less than one.

Indexed as

High-Energy Shock WavesTemperatureAnimalsMagnetic Resonance ImagingRabbitsUltrasonic Therapy

Identifiers

PMID26741344
PMCPMC4879616

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.