Evidence map›Paper›PMID 26740838›Full record

ArticleThe Pan African medical journal2015

Ethics, emergencies and Ebola clinical trials: the role of governments and communities in offshored research.

Morenike Oluwatoyin Folayan, Kristin Peterson, Frances Kombe

Abstract read
In one paragraph

Article in The Pan African medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Morenike Oluwatoyin FolayanObafemi Awolowo University, Ile-Ife, Osun State, Nigeria.
Kristin PetersonDepartment of Anthropology, University of California, Irvine, USA.
Frances KombeKEMRI Wellcome Trust Research Programme, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Ebola Virus Disease (EVD) in West Africa has stimulated investments in EVD research. While these research efforts are most welcome, we are concerned about the potential to ignore effective community ethics engagement programmes and critical government regulatory agencies in light of the urgency to conduct clinical trials for EVD therapies and vaccines. We discuss the reasons why community engagement with various research stakeholders is essential, how community engagement should be conducted, and the potential consequences of failing to engage both communities and regulatory agencies by drawing on past experiences in the field of HIV research. We highlight the importance of a) capacity building to enable local researchers design and implement EVD research for future epidemics, b) the need to support community research literacy, and c) the need to build the competency of research regulatory agencies on the continent to address EVD therapy and vaccine research.

Indexed as

Community ParticipationAfrica, WesternBiomedical ResearchCapacity BuildingClinical Trials as TopicDisease OutbreaksEbola VaccinesEmergenciesGovernment AgenciesHemorrhagic Fever, EbolaHumansEbola Vaccinescommunity engagementEbolaEthicsgovernment

Identifiers

PMID26740838
PMCPMC4695528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.