Evidence map›Paper›PMID 26739775›Full record

ArticleDental materials : official publication of the Academy of Dental Materials2016

Effect of carbodiimide on the fatigue crack growth resistance of resin-dentin bonds.

Zihou Zhang, Dylan Beitzel, Hessam Majd, Mustafa Mutluay, Arzu Tezvergil-Mutluay, Franklin R Tay, David H Pashley, Dwayne Arola

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dental materials : official publication of the Academy of Dental Materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Fatigue resistance of dentin bonds prepared with two- vs. three-step adhesives: Effect of carbodiimide.Dental materials : official publication of the Academy of Dental Materials · 2017
    Article
  6. Fatigue testing of biomaterials and their interfaces.Dental materials : official publication of the Academy of Dental Materials · 2017
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Zihou ZhangDepartment of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD, USA.
Dylan BeitzelDepartment of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD, USA.
Hessam MajdDepartment of Mechanical Engineering, University of Maryland Baltimore County, Baltimore, MD, USA.
Mustafa MutluayAdhesive Dentistry Research Group, Department of Cariology, Institute of Dentistry, University of Turku, Turku, Finland.
Arzu Tezvergil-MutluayAdhesive Dentistry Research Group, Department of Cariology, Institute of Dentistry, University of Turku, Turku, Finland.
Franklin R TayDepartment of Oral Biology, College of Dental Medicine, Georgia Health Sciences University, Augusta, GA, USA; Department of Endodontics, College of Dental Medicine, Georgia Health Sciences University, Augusta, GA, USA.
David H PashleyDepartment of Oral Biology, College of Dental Medicine, Georgia Health Sciences University, Augusta, GA, USA.
Dwayne ArolaDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, USA; Department of Restorative Dentistry, School of Dentistry, University of Washington, Seattle, WA, USA. Electronic address: darola@uw.edu.
University of Maryland, Baltimore County · USAugusta University · USUniversity of Turku · FIUniversity of Washington · US

Funding

Reasons for poor durability of resin-dentin bondsR01DE015306 · NIDCR · MEDICAL COLLEGE OF GEORGIA (MCG) · PI PASHLEY, DAVID H · 2004 to 2013
$4.4M
NIDCR NIH HHS R01 DE015306NIDCR NIH HHS R01 DE015306-06
6 · The paper itself

Abstract

unlabelledRecent studies have shown that ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) inactivates endogenous dentin proteases, thereby preventing collagen degradation and improving the durability of adhesive bonds to dentin. Bond durability is routinely assessed by monotonic microtensile testing, which does not consider the cyclic nature of mastication.

objectiveTo characterize the effect of an EDC pretreatment on the fatigue crack growth behavior of resin-dentin bonds.

methodsBonded interface Compact Tension (CT) specimens were prepared using a three-step etch-and-rinse adhesive and hybrid resin-composite. Adhesive bonding of the treated groups included a 1 min application of an experimental EDC conditioner to the acid-etched dentin. The control groups did not receive EDC treatment. The fatigue crack growth resistance was examined after storage in artificial saliva for 0, 3 and 6 months.

resultsThere was no significant difference in the immediate fatigue crack growth resistance of the EDC-treated and control groups at 0 months. However, after the 3 and 6 months storage periods the EDC-treated groups exhibited significantly greater (p≤0.05) fatigue crack growth resistance than the control specimens. SIGNIFICANCE: Although the EDC treatment maintained the fatigue crack growth resistance of the dentin bonds through 6 months of storage, additional studies are needed to assess its effectiveness over longer periods and in relation to other cross-linking agents.

Indexed as

Acid Etching, DentalAdolescentAdultCarbodiimidesComposite ResinsCross-Linking ReagentsDental Stress AnalysisDentin-Bonding AgentsHumansIn Vitro TechniquesMaterials TestingMolarResin CementsSaliva, ArtificialSilicon DioxideSurface PropertiesCarbodiimidesComposite ResinsCross-Linking ReagentsDentin-Bonding AgentsResin CementsSaliva, ArtificialScotchbond Multi-PurposeSilicon DioxideZ100 composite resinZirconiumCollagenCross-linkerDentin bonding agentsDurabilityEDCEndogenous proteinasesFatigue crack growthFracture

Identifiers

PMID26739775
PMCPMC4747783
OpenAlexW2210991603

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.