Evidence map›Paper›PMID 26739719›Full record

ArticleBMJ open2016

High prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae infections in anal and pharyngeal sites among a community-based sample of men who have sex with men and transgender women in Lima, Peru.

Segundo R Leon, Eddy R Segura, Kelika A Konda, Juan A Flores, Alfonso Silva-Santisteban, Jerome T Galea, Thomas J Coates, Jeffrey D Klausner, Carlos F Caceres

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00670163 (Comunidades Positivas and Enhanced Partner Therapy in Peru), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00670163 nacompletednot on this map

Comunidades Positivas and Enhanced Partner Therapy in Peru

TypeinterventionalSponsorUniversity of California, Los AngelesRan2008 to 2011Enrolled718ConditionsHIV Infections, Sexually Transmitted InfectionsArmsEnhanced Partner Therapy (EPT), Communidades Positivas (CPOS), Standard Care
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  6. Extra-genitalInternational journal of STD & AIDS · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Segundo R LeonLaboratory of Sexual Health and Unit of Health, Sexuality and Human Development, Cayetano Heredia University, Lima, Peru Department of Global Health, University of Washington, Seattle, Washington, USA Socios en Salud, Lima, Peru.
Eddy R SeguraEscuela de Medicina, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Kelika A KondaDivision of Infectious Diseases, School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Juan A FloresLaboratory of Sexual Health and Unit of Health, Sexuality and Human Development, Cayetano Heredia University, Lima, Peru.
Alfonso Silva-SantistebanLaboratory of Sexual Health and Unit of Health, Sexuality and Human Development, Cayetano Heredia University, Lima, Peru.
Jerome T GaleaPartners in Health, Boston, Massachusetts, USA.
Thomas J CoatesDivision of Infectious Diseases, School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Jeffrey D KlausnerDivision of Infectious Diseases, School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Carlos F CaceresLaboratory of Sexual Health and Unit of Health, Sexuality and Human Development, Cayetano Heredia University, Lima, Peru.
Universidad Peruana Cayetano Heredia · PEUniversity of California, Los Angeles · USEsSALUD · PEPartners In Health · USPeruvian University of Applied Sciences · PE

Funding

Northern/Pacific Universities Global Health Research Training ConsortiumR25TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI KOLARS, JOSEPH C., NERURKAR, VIVEK RAMCHANDRA · 2012 to 2016
$5.9M
Comunidades Positivas and Enhanced Partner Therapy in PeruR01MH078752 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI COATES, THOMAS J. · 2006 to 2010
$2.5M
Syphilis: Translating technology to understand a neglected epidemicR01AI099727 · NIAID · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI CACERES, CARLOS F. · 2012 to 2016
$1.1M
FIC NIH HHS #R25 TW009345NIAID NIH HHS R01 AI099727NIMH NIH HHS 5R01MH078752NIMH NIH HHS R01 MH078752
6 · The paper itself

Abstract

objectivesThis study aimed to characterise the epidemiology of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections among men who have sex with men (MSM) and transgender women (TW) in Lima, Peru.

settingCross-sectional study in Lima, Peru.

participantsWe recruited a group of 510 MSM and 208 TW for a subsequent community-based randomised controlled trial. The presence of CT and NG were evaluated using Aptima Combo2 in pharyngeal and anal swabs. We also explored correlates of these infections. PRIMARY AND SECONDARY OUTCOME MEASURES: Study end points included overall prevalence of C. trachomatis and N. gonorrhoeae in anal and pharyngeal sites.

resultsOverall prevalence of CT was 19% (95% CI 16.1% to 22.1%) and 4.8% (95% CI 3.3% to 6.6%) in anal and pharyngeal sites, respectively, while prevalence of NG was 9.6% (95% CI 7.5% to 12.0%) and 6.5% (95% CI 4.8% to 8.5%) in anal and pharyngeal sites, respectively.

conclusionsThe prevalence of each infection declined significantly among participants older than 34 years (p<0.05). Efforts towards prevention and treatment of extraurogenital chlamydial and gonococcal infections in high-risk populations like MSM and TW in Lima, Peru, are warranted. TRIAL REGISTRATION NUMBER: NCT00670163; Results.

Indexed as

Homosexuality, MaleTransgender PersonsAdolescentAdultAnal CanalChlamydia InfectionsChlamydia trachomatisCross-Sectional StudiesFemaleGonorrheaHumansMaleMiddle AgedNeisseria gonorrhoeaePeruPharynxPUBLIC HEALTH

Identifiers

PMID26739719
PMCPMC4716251
OpenAlexW2232042490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.