Evidence map›Paper›PMID 26739716›Full record

SynthesisBMJ open2016

Prognostic factors for disability and sick leave in patients with subacute non-malignant pain: a systematic review of cohort studies.

Gitte H Valentin, Marc S Pilegaard, Henrik B Vaegter, Marianne Rosendal, Lisbeth Ørtenblad, Ulla Væggemose, Robin Christensen

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Gitte H ValentinDepartment of Central Denmark Region, Health Technology Assessment and Health Services Research, CFK-Public Health and Quality Improvement, Aarhus, Denmark.
Marc S PilegaardDepartment of Public Health, Research Initiative for Activity Studies and Occupational Therapy, General Practice, University of Southern Denmark, Odense, Denmark.
Henrik B VaegterPain Research Group, Pain Centre South, Department of Anaesthesiology and Intensive Care Medicine, University Hospital Odense, Odense, Denmark.
Marianne RosendalResearch Unit for General Practice, Aarhus University, Denmark.
Lisbeth ØrtenbladDepartment of Central Denmark Region, Health Technology Assessment and Health Services Research, CFK-Public Health and Quality Improvement, Aarhus, Denmark.
Ulla VæggemoseDepartment of Central Denmark Region, Health Technology Assessment and Health Services Research, CFK-Public Health and Quality Improvement, Aarhus, Denmark.
Robin ChristensenMusculoskeletal Statistics Unit, Department of Rheumatology, The Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark.
Central Denmark Region · DKAarhus University · DKCopenhagen University Hospital · DKOdense University Hospital · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis systematic review aims to identify generic prognostic factors for disability and sick leave in subacute pain patients.

settingGeneral practice and other primary care facilities.

participantsAdults (>18 years) with a subacute (≤ 3-month) non-malignant pain condition. Eligibility criteria were cohort studies investigating the prediction of disability or long-term sick leave in adults with a subacute pain condition in a primary care setting. 19 studies were included, referring to a total of 6266 patients suffering from pain in the head, neck, back and shoulders. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was long-term disability (>3 months) due to a pain condition. The secondary outcome was sick leave, defined as 'absence from work' or 'return-to-work'.

resultsPubMed, EMBASE, CINAHL and PEDro databases were searched from 16 January 2003 to 16 January 2014. The quality of evidence was presented according to the GRADE WG recommendations. Several factors were found to be associated with disability at follow-up for at least two different pain symptoms. However, owing to insufficient studies, no generic risk factors for sick leave were identified.

conclusionsMultiple site pain, high pain severity, older age, baseline disability and longer pain duration were identified as potential prognostic factors for disability across pain sites. There was limited evidence that anxiety and depression were associated with disability in patients with subacute pain, indicating that these factors may not play as large a role as expected in developing disability due to a pain condition. Quality of evidence was moderate, low or very low, implying that confidence in the results is limited. Large prospective prognostic factor studies are needed with sufficient study populations and transparent reporting of all factors examined. TRIAL REGISTRATION NUMBER: CRD42014008914.

Indexed as

AbsenteeismPersons with DisabilitiesReturn to WorkSick LeaveDisability EvaluationHumansPainPrognosisEarly detectionPainPrognostic factors

Identifiers

PMID26739716
PMCPMC4716223
OpenAlexW2231119633

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.