Evidence map›Paper›PMID 26739355›Full record

ArticleJournal of autism and developmental disorders2016

Otitis Media and Related Complications Among Children with Autism Spectrum Disorders.

Daniel J Adams, Apryl Susi, Christine R Erdie-Lalena, Gregory Gorman, Elizabeth Hisle-Gorman, Michael Rajnik, Marilisa Elrod, Cade M Nylund

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Click-evoked auditory brainstem responses and autism spectrum disorder: A meta-analytic review.Autism research : official journal of the International Society for Autism Research · 2018
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Observational
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Using phecode analysis to characterize co-occurring medical conditions in autism spectrum disorder.Autism : the international journal of research and practice · 2021
    Article
  13. Article
  14. Interaction between Maternal Immune Activation and Antibiotic Use during Pregnancy and Child Risk of Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2020
    Article
  15. Co-occurring medical conditions among individuals with ASD-associated disruptive mutations.Children's health care : journal of the Association for the Care of Children's Health · 2020
    Article
  16. Review
  17. Article
  18. Infections in children with autism spectrum disorder: Study to Explore Early Development (SEED).Autism research : official journal of the International Society for Autism Research · 2019
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Daniel J AdamsDepartment of Pediatrics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA. daniel.adams@usuhs.edu.
Apryl SusiDepartment of Pediatrics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Christine R Erdie-LalenaDepartment of Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD, USA.
Gregory GormanDepartment of Pediatrics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Elizabeth Hisle-GormanDepartment of Pediatrics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Michael RajnikDepartment of Pediatrics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Marilisa ElrodDepartment of Pediatrics, Madigan Army Medical Center, Tacoma, WA, USA.
Cade M NylundDepartment of Pediatrics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Uniformed Services University of the Health Sciences · USMadigan Army Medical Center · USWalter Reed National Military Medical Center · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI MEINZEN-DERR, JAREEN, STRAWN, JEFFREY ROBERT · 2015 to 2024
$37.5M
6 · The paper itself

Abstract

Acute otitis media (AOM) symptoms can be masked by communication deficits, common to children with autism spectrum disorders (ASD). We sought to evaluate the association between ASD and otitis media. Using ICD-9-CM diagnostic codes, we performed a retrospective case-cohort study comparing AOM, and otitis-related diagnoses among children with and without ASD. Children with ASD had a significantly increased rate of AOM, otitis media with effusion, otorrhea, and PE tube placement. Children with ASD were more than twice as likely to develop mastoiditis, and to undergo mastoidectomy and tympanoplasty. Children with ASD are more likely to have middle ear infections and otitis-related complications, highlighting the importance of routine middle ear examinations and close attention to hearing impairment in this population.

Indexed as

Acute DiseaseAdolescentAutism Spectrum DisorderCase-Control StudiesChildChild, PreschoolCohort StudiesFemaleHearing LossHumansMaleMastoiditisOtitis MediaRetrospective StudiesAutism spectrum disordersChild development disorders, pervasiveMastoiditisOtitis media

Identifiers

PMID26739355
OpenAlexW2227981579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.