Evidence map›Paper›PMID 26739268›Full record

Trial reportTrials2016

Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial.

Mohammed Alim, Richard Lindley, Cynthia Felix, Dorcas Beulah Chandramathy Gandhi, Shweta Jain Verma, Deepak Kumar Tugnawat, Anuradha Syrigapu, Craig Stuart Anderson, Ramaprabhu Krishnappa Ramamurthy, Peter Langhorne and 10 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Early supported discharge services for people with acute stroke.The Cochrane database of systematic reviews · 2017
    Pooled it
  3. Caregiver-mediated exercises for improving outcomes after stroke.The Cochrane database of systematic reviews · 2016
    Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Stroke in women - from evidence to inequalities.Nature reviews. Neurology · 2017
    Review
  11. Physiotherapy in Indian communities: a brief review.Health promotion perspectives · 2017
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Mohammed AlimResearch and Development, George Institute for Global Health India, Unit 301, Second Floor ANR Centre, Road No 1, Banjara Hills, Hyderabad, Telangana, India. malim@georgeinstitute.org.in.
Richard LindleyThe George Institute for Global Health, Sydney, Australia. rlindley@georgeinstitute.org.au.
Cynthia FelixChristian Medical College, Ludhiana, Punjab, India. cfelix@georgeinstitute.org.in.
Dorcas Beulah Chandramathy GandhiChristian Medical College, Ludhiana, Punjab, India. dorcasattend@gmail.com.
Shweta Jain VermaChristian Medical College, Ludhiana, Punjab, India. sjvmv1947@gmail.com.
Deepak Kumar TugnawatIndian Institute of Public Health, Hyderabad, India. deepak.k@iiphh.org.
Anuradha SyrigapuIndian Institute of Public Health, Hyderabad, India. anuradha.s@iiphh.org.
Craig Stuart AndersonThe George Institute for Global Health, Sydney, Australia. canderson@georgeinstitute.org.au.
Ramaprabhu Krishnappa RamamurthyDepartment of Physiotherapy, Father Muller Medical College, Mangalore, India. physioram2002@gmail.com.
Peter LanghorneUniversity of Glasgow, Glasgow, UK. Peter.Langhorne@glasgow.ac.uk.
Gudlavalleti Venkata Satyanarayana MurthyIndian Institute of Public Health, Hyderabad, India. murthy.gvs@iiphh.org.
Bindiganavale Ramaswamy ShamannaSchool of Medical Sciences, University of Hyderabad, Gachibowli, Hyderabad, India. brsham@gmail.com.
Maree Lisa HackettThe George Institute for Global Health, Sydney, Australia. mhackett@georgeinstitute.org.au.
Pallab Kumar MaulikResearch and Development, George Institute for Global Health India, Unit 301, Second Floor ANR Centre, Road No 1, Banjara Hills, Hyderabad, Telangana, India. pmaulik@georgeinstitute.org.in.
Lisa Anne HarveySydney Medical School, University of Sydney, Sydney, Australia. lisa.harvey@sydney.edu.au.
Stephen JanThe George Institute for Global Health, Sydney, Australia. sjan@georgeinstitute.org.
Hueiming LiuThe George Institute for Global Health, Sydney, Australia. hliu@georgeinstitute.org.au.
Marion WalkerUniversity of Nottingham, Nottingham, UK. marion.walker@nottingham.ac.uk.
Anne ForsterUniversity of Leeds, Leeds, UK. a.forster@leeds.ac.uk.
Jeyaraj Durai PandianChristian Medical College, Ludhiana, Punjab, India. jeyarajpandian@hotmail.com.

Funding

DBT-Wellcome Trust India Alliance IA/I/13/1/500879Wellcome Trust
6 · The paper itself

Abstract

backgroundGlobally, most strokes occur in low- and middle-income countries, such as India, with many affected people having no or limited access to rehabilitation services. Western models of stroke rehabilitation are often unaffordable in many populations but evidence from systematic reviews of stroke unit care and early supported discharge rehabilitation trials suggest that some components might form the basis of affordable interventions in low-resource settings. We describe the background, history and design of the ATTEND trial, a complex intervention centred on family-led stroke rehabilitation in India. METHODS/

designThe ATTEND trial aims to test the hypothesis that a family-led caregiver-delivered home-based rehabilitation intervention, designed for the Indian context, will reduce the composite poor outcome of death or dependency at 6 months after stroke, in a multicentre, individually randomized controlled trial with blinded outcome assessment, involving 1200 patients across 14 hospital sites in India. DISCUSSION: The ATTEND trial is testing the effectiveness of a low-cost rehabilitation intervention that could be widely generalizable to other low- and middle-income countries.

trial registrationClinical Trials Registry-India CTRI/2013/04/003557 . Australian New Zealand Clinical Trials Registry ACTRN12613000078752 . Universal Trial Number U1111-1138-6707.

Indexed as

Clinical ProtocolsFamilyStroke RehabilitationCaregiversHumansIndiaOutcome Assessment, Health CareProspective StudiesSample Size

Identifiers

PMID26739268
PMCPMC4704425

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.