ArticleMagma (New York, N.Y.)2016
Investigating the state-of-the-art in whole-body MR-based attenuation correction: an intra-individual, inter-system, inventory study on three clinical PET/MR systems.
Article in Magma (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 67 citations in OpenAlex.
- Impact of improved attenuation correction on 18F-FDG PET/MR hybrid imaging of the heart.PloS one · 2019Trial
- Diagnostic Potential of Apparent Diffusion Coefficient-Based Lymph Node Classification in Breast Cancer Patients Undergoing [Diagnostics (Basel, Switzerland) · 2026Article
- International EANM-SNMMI-ISMRM consensus recommendation for PET/MRI in oncology.European journal of nuclear medicine and molecular imaging · 2023Article
- A review of PET attenuation correction methods for PET-MR.EJNMMI physics · 2023Review
- Intra-Individual Comparison ofCancers · 2022Article
- Magnetic Resonance-Based Synthetic Computed Tomography Using Generative Adversarial Networks for Intracranial Tumor Radiotherapy Treatment Planning.Journal of personalized medicine · 2022Article
- Influences on PET Quantification and Interpretation.Diagnostics (Basel, Switzerland) · 2022Review
- Cardiac PET/MR: Are sophisticated attenuation correction techniques necessary for clinical routine assessments?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- CardiovascularJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Standard MRI-based attenuation correction for PET/MRI phantoms: a novel concept using MRI-visible polymer.EJNMMI physics · 2021Article
- Accuracy and precision of zero-echo-time, single- and multi-atlas attenuation correction for dynamic [EJNMMI physics · 2020Article
- Attenuation correction for human PET/MRI studies.Physics in medicine and biology · 2020Article
- Evaluation of improved attenuation correction in whole-body PET/MR on patients with bone metastasis using various radiotracers.European journal of nuclear medicine and molecular imaging · 2020Article
- Aortic valve stenosis-multimodality assessment with PET/CT and PET/MRI.The British journal of radiology · 2020Review
- PET-derived bone information from 18F-sodium fluoride: A perfect match for whole-body PET/MR attenuation correction?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- PET/MRI attenuation estimation in the lung: A review of past, present, and potential techniques.Medical physics · 2020Review
- Assessment of attenuation correction for myocardial PET imaging using combined PET/MRI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Gating Approaches in Cardiac PET Imaging.PET clinics · 2019Review
- Dixon-VIBE Deep Learning (DIVIDE) Pseudo-CT Synthesis for Pelvis PET/MR Attenuation Correction.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019Article
- Cardiac PET/MRI-an update.European journal of hybrid imaging · 2019Review
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe assess inter- and intra-subject variability of magnetic resonance (MR)-based attenuation maps (MRμMaps) of human subjects for state-of-the-art positron emission tomography (PET)/MR imaging systems. MATERIALS AND
methodsFour healthy male subjects underwent repeated MR imaging with a Siemens Biograph mMR, Philips Ingenuity TF and GE SIGNA PET/MR system using product-specific MR sequences and image processing algorithms for generating MRμMaps. Total lung volumes and mean attenuation values in nine thoracic reference regions were calculated. Linear regression was used for comparing lung volumes on MRμMaps. Intra- and inter-system variability was investigated using a mixed effects model.
resultsIntra-system variability was seen for the lung volume of some subjects, (p = 0.29). Mean attenuation values across subjects were significantly different (p < 0.001) due to different segmentations of the trachea. Differences in the attenuation values caused noticeable intra-individual and inter-system differences that translated into a subsequent bias of the corrected PET activity values, as verified by independent simulations.
conclusionSignificant differences of MRμMaps generated for the same subjects but different PET/MR systems resulted in differences in attenuation correction factors, particularly in the thorax. These differences currently limit the quantitative use of PET/MR in multi-center imaging studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.