Evidence map›Paper›PMID 26739253›Full record

Trial reportPrevention science : the official journal of the Society for Prevention Research2016

A Comprehensive Lifestyle Intervention to Prevent Type 2 Diabetes and Cardiovascular Diseases: the German CHIP Trial.

Katharina Wennehorst, Klas Mildenstein, Brunhild Saliger, Corinna Tigges, Hans Diehl, Thomas Keil, Heike Englert

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Prevention science : the official journal of the Society for Prevention Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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  5. Article
  6. Article
  7. Design-Based Approaches to Causal Replication Studies.Prevention science : the official journal of the Society for Prevention Research · 2022
    Article
  8. Article
  9. Review
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  11. Article
  12. Review
  13. Article
  14. Patients and agents - or why we need a different narrative: a philosophical analysis.Philosophy, ethics, and humanities in medicine : PEHM · 2018
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Katharina WennehorstDepartment of Internal Medicine, Vinzenzkrankenhaus Hannover, Lange-Feld-Straße 31, 30559, Hannover, Germany. katharinawennehorst@t-online.de.
Klas MildensteinMedical practice Dr. Mildenstein, Gartenstraße 10, 30880, Laatzen, Germany.
Brunhild SaligerDepartment of Nutritional Science, University of Applied Sciences Münster, Corrensstraße 25, 48149, Münster, Germany.
Corinna TiggesDepartment of Nutritional Science, University of Applied Sciences Münster, Corrensstraße 25, 48149, Münster, Germany.
Hans DiehlLifestyle Medicine Institute, POB 8/8, Loma Linda, CA, 92354, USA.
Thomas KeilInstitute for Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Luisenstraße 57, 10117, Berlin, Germany.
Heike EnglertDepartment of Nutritional Science, University of Applied Sciences Münster, Corrensstraße 25, 48149, Münster, Germany.
FH Münster · DEReproductive Medicine Institute · USUniversity of Würzburg · DEVinzenzkrankenhaus Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of type 2 diabetes is continuously increasing. This chronic metabolic disorder is difficult to treat and imposes a considerable economic burden on the healthcare system. In view of the fact that type 2 diabetes is primarily caused by behavioral factors, effective preventive strategies are urgently needed. We examined the effects of a holistic lifestyle intervention on clinical and laboratory parameters as well as on the long-term diabetes risk in patients at risk to develop diabetes. We conducted a randomized controlled trial in a primary care setting in Hannover, Germany, with 83 patients diagnosed as (pre)diabetic or at risk for diabetes. CHIP Germany is a 40-hour coaching lifestyle intervention program for the primary and secondary prevention of type 2 diabetes and cardiovascular diseases. The intervention included a comprehensive nutrition and health educational program based on the American CHIP approach. The primary outcome parameter was the body mass index (BMI). Secondary outcome parameters included body weight, blood pressure, fasting glucose, HbA1c, blood lipids, and the FINDRISK score, which assesses long-term diabetes risk. At the final measurement after 12 months, in the intervention group the BMI was reduced by 1.4 versus 0.2 kg/m(2) in controls (p = .119). The mean sustained weight loss after 12 months was -4.1 kg in the intervention group versus -0.8 kg in controls. Furthermore, we found a trend toward a stronger reduction in blood pressure, fasting glucose, and HbA1c as well as an improved FINDRISK score in the intervention group, compared to controls. Although failing to reach statistical significance at the final assessment, this comprehensive lifestyle intervention showed a noticeable reduction in several cardiometabolic risk factors which may facilitate the prevention of diabetes.

Indexed as

Life StyleCardiovascular DiseasesDiabetes Mellitus, Type 2ExerciseFemaleGermanyHumansMaleMiddle AgedPrevalenceRisk FactorsCardiovascular riskEmpowermentHealth behaviorLifestyle coachingType 2 diabetes

Identifiers

PMID26739253
OpenAlexW2223175669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.