Evidence map›Paper›PMID 26738984›Full record

ArticleScientific reports2016

Visualisation of newly synthesised collagen in vitro and in vivo.

Corien Oostendorp, Peter J E Uijtdewilligen, Elly M Versteeg, Theo G Hafmans, Ellen H van den Bogaard, Paul K J D de Jonge, Ali Pirayesh, Johannes W Von den Hoff, Ernst Reichmann, Willeke F Daamen and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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  9. Comparison of dermal and eschar fibroblasts in full skin equivalents.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Corien OostendorpRadboud university medical center, Radboud Institute for Molecular Life Sciences, Department of Biochemistry, Nijmegen, The Netherlands.
Peter J E UijtdewilligenRadboud university medical center, Radboud Institute for Molecular Life Sciences, Department of Biochemistry, Nijmegen, The Netherlands.
Elly M VersteegRadboud university medical center, Radboud Institute for Molecular Life Sciences, Department of Biochemistry, Nijmegen, The Netherlands.
Theo G HafmansRadboud university medical center, Radboud Institute for Molecular Life Sciences, Department of Biochemistry, Nijmegen, The Netherlands.
Ellen H van den BogaardRadboud university medical center, Radboud Institute for Molecular Life Sciences, Department of Dermatology, The Netherlands.
Paul K J D de JongeRadboud university medical center, Radboud Institute for Molecular Life Sciences, Department of Urology, Nijmegen, The Netherlands.
Ali Pirayesh
Johannes W Von den HoffRadboud university medical center, Department of Orthodontics and Craniofacial Biology, Nijmegen, The Netherlands.
Ernst ReichmannUniversity Children's Hospital Zurich, Department of Surgery, Tissue Biology Research Unit, Zurich, Switzerland.
Willeke F DaamenRadboud university medical center, Radboud Institute for Molecular Life Sciences, Department of Biochemistry, Nijmegen, The Netherlands.
Toin H van KuppeveltRadboud university medical center, Radboud Institute for Molecular Life Sciences, Department of Biochemistry, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identifying collagen produced de novo by cells in a background of purified collagenous biomaterials poses a major problem in for example the evaluation of tissue-engineered constructs and cell biological studies to tumor dissemination. We have developed a universal strategy to detect and localize newly deposited collagen based on its inherent association with dermatan sulfate. The method is applicable irrespective of host species and collagen source.

Indexed as

AnimalsBiocompatible MaterialsCells, CulturedCollagenDermatan SulfateDogsFibroblastsHumansImplants, ExperimentalMiceRatsSus scrofaTissue EngineeringBiocompatible MaterialsCollagenDermatan Sulfate

Identifiers

PMID26738984
PMCPMC4704054

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.