ArticleCritical care (London, England)2016
Nutrition support practices in critically ill head-injured patients: a global perspective.
Article in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of early enteral nutrition in patients with traumatic brain injury: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Semi-elemental versus polymeric formula for enteral nutrition in brain-injured critically ill patients: a randomized trial.Critical care (London, England) · 2021Trial
- A more physiological feeding process in ICU: Intermittent infusion with semi-solid nutrients (CONSORT-compliant).Medicine · 2018Trial
- Serum-Creatinine-Estimated Augmented Renal Clearance is Associated with Marked Weight Loss after Severe Traumatic Brain Injury.Neurocritical care · 2026Article
- Gastrointestinal Dysfunction in Critically Ill Patients With Traumatic Brain Injury: Clinical Implications and Putative Mechanisms: a Narrative Review.Current neurology and neuroscience reports · 2026Review
- Barriers to nutrition following neurosurgery: A descriptive cohort study.JPEN. Journal of parenteral and enteral nutrition · 2026Article
- Patterns of Enteral Feeding, Feeding Intolerance, and Mortality in Traumatic Brain Injury: An Observational Study.Clinics and practice · 2026Article
- Predictive ability of malnutrition screening tools in enterally fed, mechanically ventilated patients with phase angle inference: A prospective observational study.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2026Article
- Development of a nutritional management protocol for patients with severe traumatic brain injury: a Delphi study.Frontiers in nutrition · 2026Article
- Enteral Nutrition Management in a Patient With Traumatic Brain Injury in the Neuro-Intensive Care Unit: A Case Report.Clinical nutrition research · 2025Article
- Protein Requirement Changes According to the Treatment Application in Neurocritical Patients.Journal of Korean Neurosurgical Society · 2024Article
- Nutrition Therapy for Patients With Traumatic Brain Injury: A Narrative Review.Korean journal of neurotrauma · 2023Review
- Nutrition Management in Patients With Traumatic Brain Injury: A Narrative Review.Brain & NeuroRehabilitation · 2022Review
- Optimizing Nitrogen Balance Is Associated with Better Outcomes in Neurocritically Ill Patients.Nutrients · 2020Article
- The Relationship between Serum Concentrations of Pro- and Anti-Inflammatory Cytokines and Nutritional Status in Patients with Traumatic Head Injury in the Intensive Care Unit.Medicina (Kaunas, Lithuania) · 2019Article
- Effects of sequential nutritional support on nutritional status and expression of regulatory T lymphocyte in patients with early severe traumatic brain injury.Neuropsychiatric disease and treatment · 2018Article
- Nutritional and Bioenergetic Considerations in Critically Ill Patients with Acute Neurological Injury.Neurocritical care · 2017Review
- Effect of Calories Delivered on Clinical Outcomes in Critically Ill Patients: Systemic Review and Meta-analysis.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCritical illness following head injury is associated with a hypermetabolic state but there are insufficient epidemiological data describing acute nutrition delivery to this group of patients. Furthermore, there is little information describing relationships between nutrition and clinical outcomes in this population.
methodsWe undertook an analysis of observational data, collected prospectively as part of International Nutrition Surveys 2007-2013, and extracted data obtained from critically ill patients with head trauma. Our objective was to describe global nutrition support practices in the first 12 days of hospital admission after head trauma, and to explore relationships between energy and protein intake and clinical outcomes. Data are presented as mean (SD), median (IQR), or percentages.
resultsData for 1045 patients from 341 ICUs were analyzed. The age of patients was 44.5 (19.7) years, 78% were male, and median ICU length of stay was 13.1 (IQR 7.9-21.6) days. Most patients (94%) were enterally fed but received only 58% of estimated energy and 53% of estimated protein requirements. Patients from an ICU with a feeding protocol had greater energy and protein intakes (p <0.001, 0.002 respectively) and were more likely to survive (OR 0.65; 95% CI 0.42-0.99; p = 0.043) than those without. Energy or protein intakes were not associated with mortality. However, a greater energy and protein deficit was associated with longer times until discharge alive from both ICU and hospital (all p <0.001).
conclusionNutritional deficits are commonplace in critically ill head-injured patients and these deficits are associated with a delay to discharge alive.
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