Evidence map›Paper›PMID 26738505›Full record

ArticleEuropean radiology2016

Can prostatic arterial embolisation (PAE) reduce the volume of the peripheral zone? MRI evaluation of zonal anatomy and infarction after PAE.

Yen-Ting Lin, Grégory Amouyal, Jean-Michel Correas, Héléna Pereira, Olivier Pellerin, Costantino Del Giudice, Carole Déan, Nicolas Thiounn, Marc Sapoval

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In one paragraph

Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yen-Ting LinAssistance publique Hôpitaux de Paris. Hôpital Européen Georges-Pompidou, Vascular and Oncological Interventional Radiology, 20 rue Leblanc, 75015, Paris, France. ymerically@gmail.com.
Grégory AmouyalAssistance publique Hôpitaux de Paris. Hôpital Européen Georges-Pompidou, Vascular and Oncological Interventional Radiology, 20 rue Leblanc, 75015, Paris, France.
Jean-Michel CorreasAssistance publique Hôpitaux de Paris. Hôpital Européen Georges-Pompidou, Vascular and Oncological Interventional Radiology, 20 rue Leblanc, 75015, Paris, France.
Héléna PereiraAssistance publique Hôpitaux de Paris. Hôpital Européen Georges-Pompidou, Vascular and Oncological Interventional Radiology, 20 rue Leblanc, 75015, Paris, France.
Olivier PellerinAssistance publique Hôpitaux de Paris. Hôpital Européen Georges-Pompidou, Vascular and Oncological Interventional Radiology, 20 rue Leblanc, 75015, Paris, France.
Costantino Del GiudiceAssistance publique Hôpitaux de Paris. Hôpital Européen Georges-Pompidou, Vascular and Oncological Interventional Radiology, 20 rue Leblanc, 75015, Paris, France.
Carole DéanAssistance publique Hôpitaux de Paris. Hôpital Européen Georges-Pompidou, Vascular and Oncological Interventional Radiology, 20 rue Leblanc, 75015, Paris, France.
Nicolas ThiounnAssistance publique Hopitaux de Paris, Hôpital Européen Georges-Pompidou, Urology, 20 rue Leblanc, 75015, Paris, France.
Marc SapovalAssistance publique Hôpitaux de Paris. Hôpital Européen Georges-Pompidou, Vascular and Oncological Interventional Radiology, 20 rue Leblanc, 75015, Paris, France.
Hôpital Européen Georges-Pompidou · FRHôpital Européen · FRHôpital Necker-Enfants Malades · FRSorbonne Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the impact of prostatic arterial embolisation (PAE) on various prostate gland anatomical zones.

methodsWe retrospectively reviewed paired MRI scans obtained before and after PAE for 25 patients and evaluated changes in volumes of the median lobe (ML), central gland (CG), peripheral zone (PZ) and whole prostate gland (WPV) following PAE. We used manual segmentation to calculate volume on axial view T2-weighted images for ML, CG and WPV. We calculated PZ volume by subtracting CG volume from WPV. Enhanced phase on dynamic contrasted-enhanced MRI was used to evaluate the infarction areas after PAE. Clinical results of International Prostate Symptom Score and International Index of Erectile Function questionnaires and the urodynamic study were evaluated before and after PAE.

resultsSignificant reductions in volume were observed after PAE for ML (26.2 % decrease), CG (18.8 %), PZ (16.4 %) and WPV (19.1 %; p < 0.001 for all these volumes). Patients with clinical failure had smaller volume reductions for WPV, ML and CG (all p < 0.05). Patients with significant CG infarction after PAE displayed larger WPV, ML and CG volume reductions (all p < 0.01).

conclusionsPAE can significantly decrease WPV, ML, CG and PZ volumes, and poor clinical outcomes are associated with smaller volume reductions. KEY POINTS: • The MRI segmentation method provides detailed comparisons of prostate volume change. • Prostatic arterial embolisation (PAE) decreased central gland and peripheral zone volumes. • Prostates with infarction after PAE showed larger decreases in volume. • A larger decrease in prostate volume is associated with clinical success.

Indexed as

AgedContrast MediaEmbolization, TherapeuticHumansImage EnhancementInfarctionMagnetic Resonance ImagingMaleMiddle AgedOrgan SizeProstateProstatic HyperplasiaRetrospective StudiesTreatment OutcomeContrast MediaAnatomy, cross-sectionalBenign prostatic hyperplasiaMagnetic resonance imagingProstateTherapeutic embolisation

Identifiers

PMID26738505
OpenAlexW2231286800

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.