Evidence map›Paper›PMID 26738503›Full record

ReviewNeurocritical care2016

The Insertion and Management of External Ventricular Drains: An Evidence-Based Consensus Statement : A Statement for Healthcare Professionals from the Neurocritical Care Society.

Herbert I Fried, Barnett R Nathan, A Shaun Rowe, Joseph M Zabramski, Norberto Andaluz, Adarsh Bhimraj, Mary McKenna Guanci, David B Seder, Jeffrey M Singh

Registry-linked trialAbstract readReviewConsensus Statement
PubMed Publisher
In one paragraph

Review in Neurocritical care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06772155 (A Comparative Effectiveness Study on Catheter Locking Device Versus Standard Ventriculostomy for Surgical Management of Traumatic Brain Injury Patients With Intracranial Compartment Syndrome), which is not on this map. Cited by 132 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 11 pooled it
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06772155 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Comparative Effectiveness Study on Catheter Locking Device Versus Standard Ventriculostomy for Surgical Management of Traumatic Brain Injury Patients With Intracranial Compartment Syndrome

Typeobservational_patient_registrySponsorMeditech FoundationRan2025 to 2027Enrolled292ConditionsTraumatic Brain Injuries, Intracranial HypertensionArmsVentriculostomy, Ventriculostomy + Locking Device
3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 11 syntheses or guidelines pooled it, 331 citations in OpenAlex.

  1. Routine versus clinically indicated cerebrospinal fluid sampling for infection in external ventricular drains: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 2 countries.

Herbert I FriedUniversity of Colorado and Denver Health Medical Center, Denver, CO, USA.
Barnett R NathanUniversity of Virginia, Charlottesville, VA, USA. brn3a@virginia.edu.
A Shaun RoweCollege of Pharmacy, University of Tennessee Health Science Center, Knoxville, TN, USA.
Joseph M ZabramskiBarrow Neurological Institute, Phoenix, AZ, USA.
Norberto AndaluzUniversity of Cincinnati College of Medicine, University of Cincinnati Neuroscience Institute and Mayfield Clinic, Cincinnati, OH, USA.
Adarsh BhimrajCleveland Clinic, Cleveland, OH, USA.
Mary McKenna GuanciMassachusetts General Hospital, Boston, MA, USA.
David B SederDepartment of Critical Care Services, Maine Medical Center, Portland, ME, USA.
Jeffrey M SinghDepartment of Medicine, University of Toronto and Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Canada.
Barrow Neurological Institute · USCleveland Clinic · USMaine Medical Center · USMassachusetts General Hospital · USToronto Western Hospital · CAUniversity of Cincinnati Medical Center · USUniversity of Colorado Denver · USUniversity of Tennessee Health Science Center · USUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

External ventricular drains (EVDs) are commonly placed to monitor intracranial pressure and manage acute hydrocephalus in patients with a variety of intracranial pathologies. The indications for EVD insertion and their efficacy in the management of these various conditions have been previously addressed in guidelines published by the Brain Trauma Foundation, American Heart Association and combined committees of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons. While it is well recognized that placement of an EVD may be a lifesaving intervention, the benefits can be offset by procedural and catheter-related complications, such as hemorrhage along the catheter tract, catheter malposition, and CSF infection. Despite their widespread use, there are a lack of high-quality data regarding the best methods for placement and management of EVDs to minimize these risks. Existing recommendations are frequently based on observational data from a single center and may be biased to the authors' view. To address the need for a comprehensive set of evidence-based guidelines for EVD management, the Neurocritical Care Society organized a committee of experts in the fields of neurosurgery, neurology, neuroinfectious disease, critical care, pharmacotherapy, and nursing. The Committee generated clinical questions relevant to EVD placement and management. They developed recommendations based on a thorough literature review using the Grading of Recommendations Assessment, Development, and Evaluation system, with emphasis placed not only on the quality of the evidence, but also on the balance of benefits versus risks, patient values and preferences, and resource considerations.

Indexed as

ConsensusCritical CareDrainageEvidence-Based MedicineHumansNeurologySocieties, MedicalVentriculostomyAntibiotic coated catheterAntibiotic prophylaxisAntibioticsAntimicrobial coated catheterCSF drainageDeep venous thrombosisDVTDVT prophylaxisEVDExternal ventricular drainHemorrhageHydrocephalusICPIntraventricular antibioticsMonitoringThromboembolismVAIVentriculostomyVentriculostomy associated infectionVentriculostomy-related infectionVRI

Identifiers

PMID26738503
OpenAlexW2229146891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.