ReviewAnnual review of pharmacology and toxicology2016
Triclosan: A Widespread Environmental Toxicant with Many Biological Effects.
Review in Annual review of pharmacology and toxicology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
84 citing papers in PubMed, 1 synthesis or guideline pooled it, 317 citations in OpenAlex.
- Assessment of ovarian dysfunction induced by environmental toxins: a systematic review.Frontiers in public health · 2025Pooled it
- Potential molecular links between triclosan exposure and osteoarthritis: An integrative systems toxicology study.iScience · 2026Article
- Associations of Urinary Triclosan Concentrations Across Gestation and Childhood with the Adolescent Gut Microbiome.Environmental health perspectives · 2026Article
- Magnetic porous reduced graphene oxide-based dispersive solid phase extraction for triclosan quantification in water.iScience · 2026Article
- Resveratrol protects against triclosan-induced impairment of colonic barrier function in chickens.Poultry science · 2026Article
- Itching to know: the Microbiome, Allergic Disease, and Antimicrobial Chemicals.Current environmental health reports · 2026Review
- Dynamics of Endocrine Disruptor Exposure in Early Life: A Mother-Infant Hair Biomonitoring Study.Toxics · 2026Article
- An aryloxyphenol potentiates polymyxin against multidrug-resistantFrontiers in cellular and infection microbiology · 2026Article
- Article
- Metabolome informs about the chemical exposome and links to brain health.Environment international · 2025Review
- A review of advancements in antiseptics for wound care in diabetic and non-diabetic patients.Journal of diabetes and metabolic disorders · 2025Review
- Mucin Coatings Establish Multifunctional Properties on Commercial Sutures.ACS applied bio materials · 2025Article
- Effective adsorptive removal of triclosan from water using bio-nanocomposite hydrogel beads.Frontiers in chemistry · 2025Article
- Microbes as Resources to Remove PPCPs and Improve Water Quality.Microbial biotechnology · 2025Review
- Prenatal exposure to endocrine-disrupting chemicals and childhood atopic dermatitis: epidemiological evidence.Frontiers in microbiology · 2025Review
- Article
- Essential Oil-Based Soap with Clove and Oregano: A Promising Antifungal and Antibacterial Alternative against Multidrug-Resistant Microorganisms.Molecules (Basel, Switzerland) · 2024Article
- Removal of contaminants of emerging concern by Wolffia arrhiza and Lemna minor depending on the process conditions, pollutants concentration, and matrix type.Scientific reports · 2024Article
- The Highly Durable Antibacterial Gel-like Coatings for Textiles.Gels (Basel, Switzerland) · 2024Article
- Medical Device-Associated Biofilm Infections and Multidrug-Resistant Pathogens.Pathogens (Basel, Switzerland) · 2024Review
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Triclosan (TCS) is a broad-spectrum antimicrobial agent that has been added to personal care products, including hand soaps and cosmetics, and impregnated in numerous different materials ranging from athletic clothing to food packaging. The constant disposal of TCS into the sewage system is creating a major environmental and public health hazard. Owing to its chemical properties of bioaccumulation and resistance to degradation, TCS is widely detected in various environmental compartments in concentrations ranging from nanograms to micrograms per liter. Epidemiology studies indicate that significant levels of TCS are detected in body fluids in all human age groups. We document here the emerging evidence--from in vitro and in vivo animal studies and environmental toxicology studies--demonstrating that TCS exerts adverse effects on different biological systems through various modes of action. Considering the fact that humans are simultaneously exposed to TCS and many TCS-like chemicals, we speculate that TCS-induced adverse effects may be relevant to human health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.