ArticleAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2015
A 3-D admittance-level computational model of a rat hippocampus for improving prosthetic design.
Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Adaptive octree meshes for simulation of extracellular electrophysiology.Journal of neural engineering · 2023Article
- Admittance Method for Estimating Local Field Potentials Generated in a Multi-Scale Neuron Model of the Hippocampus.Frontiers in computational neuroscience · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Hippocampal prosthetic devices have been developed to bridge the gap between functioning portions of the hippocampus, in order to restore lost memory functionality in those suffering from brain injury or diseases. One approach taken in recent neuroprosthetic design is to use a multi-input, multi-output device that reads data from the CA3 in the hippocampus and electrically stimulates the CA1 in an attempt to mimic the appropriate firing pattern that would occur naturally between the two areas. However, further study needs to be conducted in order to optimize electrode placement, pulse magnitude, and shape for creating the appropriate firing pattern. This paper describes the creation and implementation of an anatomically correct 3D model of the hippocampus to simulate the electric field patterns and axonal activation from electrical stimulation due to an implanted electrode array. The activating function was applied to the voltage results to determine the firing patterns in possible axon locations within the CA1.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.