Evidence map›Paper›PMID 26736134›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2016

Relationship Between Near-Infrared Spectroscopy and Transabdominal Ultrasonography: Noninvasive Monitoring of Intestinal Function in Neonates.

Devang H Akotia, Jayson T Durham, Kathy M Arnell, Deborah L Petruzzelli, Anup C Katheria

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Feeding intolerance.Early human development · 2022
    Article
  6. Article
  7. Review
  8. Differential effects of the retinopathy of prematurity exam on the physiology of premature infants.Journal of perinatology : official journal of the California Perinatal Association · 2019
    Article
  9. Article
  10. Splanchnic NIRS monitoring in neonatal care: rationale, current applications and future perspectives.Journal of perinatology : official journal of the California Perinatal Association · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Devang H AkotiaNeonatal Research Institute, Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA, USA.
Jayson T DurhamNeonatal Research Institute, Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA, USA.
Kathy M ArnellNeonatal Research Institute, Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA, USA.
Deborah L PetruzzelliNeonatal Research Institute, Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA, USA.
Anup C KatheriaNeonatal Research Institute, Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA, USA.
Sharp Mary Birch Hospital for Women & Newborns · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNear-infrared spectroscopy (NIRS) has the potential to continuously and noninvasively monitor intestinal function. This technology may be valuable because among neonates, intestinal maturity is highly variable and difficult to assess based solely on clinical signs. The aim of this study was to determine if there is an association between NIRS-based StO2 measurements and peristaltic activity assessed by transabdominal ultrasonography (US). MATERIAL/

methodsNineteen neonates of gestational age >32 weeks were categorized according to "no/low" versus "normal/hyperactive" motility levels, based on blinded US scan results. StO2 was recorded every 2 s for 24 h, following the ultrasound recording. Differences between the resulting estimates of average StO2 (bias of fits) and goodness-of-fit (residuals) were evaluated.

resultsNewborns with normal/hyperactive motility had higher mean StO2 than newborns with no/low motility (72.3±4.4 vs. 65.5±7.9, p<0.05, F=5.65). Residual errors were not significantly different between the 2 groups (p=0.213, F=0.213). A multivariate linear regression model using the means, residuals, and pairwise products of both, demonstrated more significant separation (0.47±0.26 vs. -0.24±0.33, p<0.01, F=27.4). A non-linear variant of the multivariate linear regression model demonstrated greatest separation (0.68±0.24 vs. -0.49±0.53, p<0.01, F=41.9).

conclusionsThis is the first study to demonstrate an association between NIRS-based StO2 measurements and peristaltic activity visualized by ultrasound imaging. NIRS may offer a continuous, noninvasive method to assess motility. This may have significant implications in premature infants at risk for feeding intolerance or necrotizing enterocolitis.

Indexed as

Spectroscopy, Near-InfraredUltrasonographyEnterocolitis, NecrotizingFemaleGastrointestinal MotilityHumansInfant, NewbornInfant, Premature, DiseasesIntestinesMaleMonitoring, PhysiologicMultivariate AnalysisNeonatologyOximetryOxygenPeristalsisOxygen

Identifiers

PMID26736134
PMCPMC4708098
OpenAlexW2224209798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.