ArticlePloS one2016
Evaluation of Infectivity, Virulence and Transmission of FDMV Field Strains of Serotypes O and A Isolated In 2010 from Outbreaks in the Republic of Korea.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A meta-analysis on the effectiveness of serotype O foot-and-mouth disease vaccines.Scientific reports · 2025Pooled it
- Attenuation without protective immunogenicity: effects of codon-pair deoptimization on foot-and-mouth disease virus serotype O in swine.Scientific reports · 2026Article
- The pathogenesis of foot-and-mouth disease virus: current understandings and knowledge gaps.Veterinary research · 2025Review
- Controlling endemic foot-and-mouth disease: Vaccination is more important than movement bans. A simulation study in the Republic of Turkey.Infectious Disease Modelling · 2025Article
- Epidemiologic consequences of preclinical transmission of foot-and-mouth disease virus in cattle.Frontiers in veterinary science · 2025Article
- Article
- A Meta-Population Model of Potential Foot-and-Mouth Disease Transmission, Clinical Manifestation, and Detection Within U.S. Beef Feedlots.Frontiers in veterinary science · 2020Article
- Duration of Contagion of Foot-And-Mouth Disease Virus in Infected Live Pigs and Carcasses.Frontiers in veterinary science · 2020Article
- Endemic foot and mouth disease: pastoral in-herd disease dynamics in sub-Saharan Africa.Scientific reports · 2019Article
- Virulence beneath the fleece; a tale of foot-and-mouth disease virus pathogenesis in sheep.PloS one · 2019Article
- Parameterization of the Durations of Phases of Foot-And-Mouth Disease in Cattle.Frontiers in veterinary science · 2019Article
- Transmission of Foot-and-Mouth Disease Virus during the Incubation Period in Pigs.Frontiers in veterinary science · 2016Article
- The Pathogenesis of Foot-and-Mouth Disease in Pigs.Frontiers in veterinary science · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the early 2000s outbreaks of foot-and-mouth disease (FMD) have been described in several previously FMD-free Asian nations, including the Republic of Korea (South Korea). One outbreak with FMD virus (FDMV) serotype A and two with serotype O occurred in South Korea in 2010/2011. The causative viruses belonged to lineages that had been spreading in South East Asia, far East and East Asia since 2009 and presented a great threat to the countries in that region. Most FMDV strains infect ruminants and pigs, as it happened during the outbreaks of FMDV serotype O in South Korea. Contrastingly, the strain of serotype A affected only ruminants. Based upon these findings, the intention of the work described in the current report was to characterize and compare the infectivity, virulence and transmission of both strains under laboratory conditions in cattle and pigs, by direct inoculation and contact exposure. As expected, FMDV serotype O was highly virulent in both cattle and swine by contact exposure and direct inoculation. Surprisingly, FMDV serotype A was highly virulent in swine, but was less infectious in cattle by contact exposure to infected swine or cattle. Interestingly, similar quantities of aerosolized FMDV RNA were detected during experiments with viruses of serotypes O and A. Specific virus-host interaction of A/SKR/2010 could affect the transmission of this strain to cattle, and this may explain in part the limited spread of the serotype A epizootic.
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